专题：Hemoglobin structure and function

This cluster of papers focuses on the function, regulation, and physiological impact of hemoglobin and related proteins in vertebrates. It covers topics such as scavenger receptor CD163 expression, neuroglobin and myoglobin function, haptoglobin phenotype, nitric oxide dioxygenase activity, and the role of flavohemoglobins in detoxifying nitric oxide. The papers also discuss the use of hemoglobin-based oxygen carriers and their potential impact on cardiovascular disease.
最新文献
Enhanced γ-globin reactivation and sickle cell correction through a repressor-to-activator motif switch in the HBG1/2 promoters

article Full Text OpenAlex

The red blood cell proteome and interactome identify a Band 3–BLVRB axis regulating hypoxic metabolic adaptation

article Full Text OpenAlex

A Functional Model of Diiron Nitrite Reductases: Overcoming Catalyst Poisoning in the Diiron-Mediated Catalytic Reduction of Nitrite to Nitric Oxide

article Full Text OpenAlex

Regulatory interplay between nitric oxide and heme in redox signaling and inflammation

review Full Text OpenAlex

Metal–organic frameworks for the fabrication of hemoglobin-based oxygen carriers: A comprehensive review

review Full Text OpenAlex

Protein Arginine Methyltransferases in γ-Globin Regulation and Sickle Cell Disease: Emerging Connections to Oxidative Stress

review Full Text OpenAlex

Oxidative Dynamics of Frigate Mackerel (Auxis thazard) Myoglobin Model System Mediated by Kratom (Mitragyna speciosa) Leaf Polyphenol Extract: Implications for Heme Stability and Color Preservation

article Full Text OpenAlex

Heme oxygenase-1 and malaria pathogenesis

review Full Text OpenAlex

Current research on the HIF-2α-EPO–Hb axis in hypoxic environments: from molecular mechanisms to clinical

review Full Text OpenAlex

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

review Full Text OpenAlex

近5年高被引文献
Nitric oxide signaling in health and disease

review Full Text OpenAlex 837 FWCI22.2836

Sickle Cell Disease

review Full Text OpenAlex 482 FWCI14.5656

Molecular Mechanisms of Iron and Heme Metabolism

review Full Text OpenAlex 325 FWCI10.6095

Heme Oxygenase-1: An Anti-Inflammatory Effector in Cardiovascular, Lung, and Related Metabolic Disorders

review Full Text OpenAlex 274 FWCI5.6711

Erythrocyte Structure and Function

other Full Text OpenAlex 198 FWCI0

Hemolysis, free hemoglobin toxicity, and scavenger protein therapeutics

article Full Text OpenAlex 167 FWCI16.055

Understanding Sickle cell disease: Causes, symptoms, and treatment options

review Full Text OpenAlex 165 FWCI7.7974

Second Sphere Effects on Oxygen Reduction and Peroxide Activation by Mononuclear Iron Porphyrins and Related Systems

review Full Text OpenAlex 148 FWCI0.9174

The hemoglobinopathies, molecular disease mechanisms and diagnostics

review Full Text OpenAlex 108 FWCI3.1953

Nitric Oxide Signaling and Regulation in the Cardiovascular System: Recent Advances

review Full Text OpenAlex 103 FWCI5.9626