专题:Chemical Reaction Mechanisms

This cluster of papers explores nucleophilic reactivity in organic chemistry, covering topics such as nucleophilicity scales, acidity scales, phosphate hydrolysis mechanisms, enzymatic mechanisms, superbases for organic synthesis, electrophilicity parameters, aminolysis reactions, transition state analysis, hydride transfer reactions, and their applications in organic synthesis.
最新文献
Recent advances in the deuteration of indoles

article Full Text OpenAlex

Iodine‐Mediated [2+2+1+1] Annulation Using N , N ‐Dimethylformamide as a One‐Carbon Synthon: Access to Pyridine and Triazine Scaffolds

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Enhanced utilization of ester enolates in slow-kinetic α-functionalization of esters: Insights into enolate consumption and preservation strategies

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From NH + Chemical Shifts to Chemical Insights: A 1 H NMR Spectroscopic Window into Amine p K a , Anion p K BHX, and Charge-Assisted Intramolecular H-Bond Assessment from a Medicinal Chemistry Perspective

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Messy Chemistry and the Emergence of Life

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Synthesis of Pyrazole-Fused Heterocyclic N -Nitroacetamides with High Energy and Low Sensitivity

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Regioselectivity of the SEAr reaction of 8-chloro-3,4-dihydro-1H-[1,4]oxazino[4,3-a]benzimidazole

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Indole Scaffolds in Neurological Therapeutics: Synthesis, Structure-Activity Relationships and Drug-Receptor Interactions

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Synthesis of Peptides, Peptide Nucleic Acid Components, and Other Biogenic Compounds From a Three‐Component Prebiotic Mixture

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Scope of Nitrostyrenes in Chemistry and Biology and the Advancement of Their Reactions

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近5年高被引文献
An Update on the Nitrogen Heterocycle Compositions and Properties of U.S. FDA-Approved Pharmaceuticals (2013–2023)

review Full Text OpenAlex 741 FWCI173.0405

Pyridine: the scaffolds with significant clinical diversity

review Full Text OpenAlex 299 FWCI28.7423

Current Topics on Chemistry and Biochemistry Vol. 1

book Full Text OpenAlex 244 FWCI90.492

“Magic Chloro”: Profound Effects of the Chlorine Atom in Drug Discovery

review Full Text OpenAlex 234 FWCI25.5641

Replacement of Less-Preferred Dipolar Aprotic and Ethereal Solvents in Synthetic Organic Chemistry with More Sustainable Alternatives

review Full Text OpenAlex 182 FWCI18.0105

Forever young: the first seventy years of ferrocene

review Full Text OpenAlex 141 FWCI14.6953

Electrophilicity index revisited

review Full Text OpenAlex 140 FWCI12.3967

Cyrene: a bio-based novel and sustainable solvent for organic synthesis

article Full Text OpenAlex 124 FWCI11.9678

Density functional theory, chemical reactivity, and the Fukui functions

article Full Text OpenAlex 121 FWCI11.4092

Electrophilicity and nucleophilicity scales at different DFT computational levels

article Full Text OpenAlex 117 FWCI16.8882