专题：Chemical Reaction Mechanisms

This cluster of papers explores nucleophilic reactivity in organic chemistry, covering topics such as nucleophilicity scales, acidity scales, phosphate hydrolysis mechanisms, enzymatic mechanisms, superbases for organic synthesis, electrophilicity parameters, aminolysis reactions, transition state analysis, hydride transfer reactions, and their applications in organic synthesis.
最新文献
Deciphering the Impact of Mutations on PfDHPS Active Site and Sulfadoxine Binding: Structural Insights from Molecular Dynamics Simulations

article Full Text OpenAlex

An Update on the Nitrogen Heterocycle Compositions and Properties of U.S. FDA-Approved Pharmaceuticals (2013–2023)

review Full Text OpenAlex

Cryogenic Rearrangements of Spiroheptadiyl: Light- or Heavy-Atom Quantum Tunneling?

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Acid-base properties of hydroxyquinolines in aqueous solution: Effect of hydroxyl group position on thermodynamic protonation parameters

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Binding of Sulfates and Water to Monovalent Cations

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Enhanced dynamic coupling in a nuclear receptor underlies ligand activity

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Deprotonation of 8-Oxo-7,8-dihydroadenine Radical Cation in Free and Encumbered Context: A Theoretical Study

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Synthesis, X-ray characterization, and DFT study of six deferiprone analogues

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Kinetics of reduction of m‐iodonitrobenzene by aqueous ammonium sulfide under liquid–liquid phase transfer catalysis

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A density functional theory study of keto-enol tautomerism in 1,2-cyclodiones: Substituent effects on reactivity and thermodynamic stability

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近5年高被引文献
Use of molecular docking computational tools in drug discovery

review Full Text OpenAlex 525 FWCI180.15219515

Water as the reaction medium in organic chemistry: from our worst enemy to our best friend

review Full Text OpenAlex 486 FWCI51.77276994

An Update on the Nitrogen Heterocycle Compositions and Properties of U.S. FDA-Approved Pharmaceuticals (2013–2023)

review Full Text OpenAlex 485 FWCI211.30726893

Pyridine: the scaffolds with significant clinical diversity

review Full Text OpenAlex 252 FWCI43.33086163

Current Topics on Chemistry and Biochemistry Vol. 1

book Full Text OpenAlex 244 FWCI72.06217621

“Magic Chloro”: Profound Effects of the Chlorine Atom in Drug Discovery

review Full Text OpenAlex 179 FWCI32.80399945

Strengths of Acids in Acetonitrile

article Full Text OpenAlex 177 FWCI17.38187598

Replacement of Less-Preferred Dipolar Aprotic and Ethereal Solvents in Synthetic Organic Chemistry with More Sustainable Alternatives

review Full Text OpenAlex 153 FWCI22.6130306

Stereoelectronic power of oxygen in control of chemical reactivity: the anomeric effect is not alone

review Full Text OpenAlex 151 FWCI12.98348661

Forever young: the first seventy years of ferrocene

review Full Text OpenAlex 127 FWCI21.83737868