专题：Chemical Reaction Mechanisms

This cluster of papers explores nucleophilic reactivity in organic chemistry, covering topics such as nucleophilicity scales, acidity scales, phosphate hydrolysis mechanisms, enzymatic mechanisms, superbases for organic synthesis, electrophilicity parameters, aminolysis reactions, transition state analysis, hydride transfer reactions, and their applications in organic synthesis.
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Enrichment and Kinetic Profiling of

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Quantum chemical study on the activity of organic superbase phosphazene t-Bu-P4/DMSO in the autocondensation reaction of ketones

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Development of radiolabeling 2-oxo-2-(4-phenylpiperazin-1-yl)acetamide derivatives as potential molecular probes for excitatory amino acid transporter 2

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Achiral NaI and 2-Mercaptobenzimidazole as Chiral Modulators for Stereodivergent Synthesis of Azanucleosides

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Substituent Effect on the Nucleophilic Aromatic Substitution of Thiophenes With Pyrrolidine: Theoretical Mechanistic and Reactivity Study

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Metal-Controlled Nuclearity in Phenol-Based Symmetric “End-Off” Compartmental Ligands Mediated by Acetate Anions: A DFT Study to Rationalize Their Formation

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Integrated experimental and in silico studies on thiophene carboxamide derivatives: synthesis, characterization, and biological evaluation

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Kinetic and structural evidence for specific DMSO interference with reversible binding of uncharged bis-oximes to hAChE and their reactivation kinetics of OP-hAChE.

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Phase transition and chemical stability of s-Triazine under static and dynamic compression

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Estimation of the Composition of Nitro-Aci forms of Nitromethane Tautomerism by Refrachor (F) an Old Tool for a New Contemporary Observation

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近5年高被引文献
Use of molecular docking computational tools in drug discovery

review Full Text OpenAlex 431 FWCI7.917

Water as the reaction medium in organic chemistry: from our worst enemy to our best friend

review Full Text OpenAlex 416 FWCI7.862

Pyridine: the scaffolds with significant clinical diversity

review Full Text OpenAlex 176 FWCI5.923

An Update on the Nitrogen Heterocycle Compositions and Properties of U.S. FDA-Approved Pharmaceuticals (2013–2023)

review Full Text OpenAlex 165 FWCI40.628

Strengths of Acids in Acetonitrile

article Full Text OpenAlex 145 FWCI12.332

Stereoelectronic power of oxygen in control of chemical reactivity: the anomeric effect is not alone

review Full Text OpenAlex 120 FWCI3.252

Replacement of Less-Preferred Dipolar Aprotic and Ethereal Solvents in Synthetic Organic Chemistry with More Sustainable Alternatives

review Full Text OpenAlex 118 FWCI3.071

“Magic Chloro”: Profound Effects of the Chlorine Atom in Drug Discovery

review Full Text OpenAlex 117 FWCI5.955

Forever young: the first seventy years of ferrocene

review Full Text OpenAlex 99 FWCI3.47

N‐Atom Deletion in Nitrogen Heterocycles

article Full Text OpenAlex 90 FWCI7.515