专题：Chemical Reaction Mechanisms

This cluster of papers explores nucleophilic reactivity in organic chemistry, covering topics such as nucleophilicity scales, acidity scales, phosphate hydrolysis mechanisms, enzymatic mechanisms, superbases for organic synthesis, electrophilicity parameters, aminolysis reactions, transition state analysis, hydride transfer reactions, and their applications in organic synthesis.
最新文献
Mechanistic Study of N‐t‐Butyl Nitrone and Nitroethene (3 + 2) Cycloaddition: A Combined DFT, Docking, and ADMET Approach

article Full Text OpenAlex

An energetic study of differences in crystallization of N-(furan-3-yl)benzamide and N-(thiophen-3-yl)benzamide

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Intramolecular hydrogen bonding in 1,8-bis(dimethylamino)naphthalenes containing two to four heteroatomic functions in the ortho- and peri-positions: from CD3 to sulfur and selenium

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Unraveling the Substituent Impact of Fluorinated & Oxidized Sumanene Derivatives on Stacking Interactions and Charge Transport

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Trimetazidine–Profen Hybrid Molecules: Synthesis, Chemical Characterization, and Biological Evaluation of Their Racemates

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Review for "Unveiling the migration reactivity of bicyclic diaziridines: enantioselective synthesis of chiral pyrazolines"

peer-review Full Text OpenAlex

[2.2.1]Heterobicyclic Bromovinyl Sulfones for Thiol-Triggered Strategies in Linker Chemistry: Aza- vs Oxa-Norbornadienic Systems

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Halogen anion (Cl−, Br−) and alkali metal cation (Cs+, K+, Rb+) synergistic binding behaviors using a belt shaped dual-functional hydrocarbon receptor

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Quantum-Chemical Modelling of Adenosine Triphosphate Hydrolysis in Water Medium

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Orientation of nitration in bay-region of benzothioxanthene imide: A streamlined pathway to N- and S-annulated derivatives

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近5年高被引文献
Use of molecular docking computational tools in drug discovery

review Full Text OpenAlex 449 FWCI7.947

Water as the reaction medium in organic chemistry: from our worst enemy to our best friend

review Full Text OpenAlex 430 FWCI7.846

An Update on the Nitrogen Heterocycle Compositions and Properties of U.S. FDA-Approved Pharmaceuticals (2013–2023)

review Full Text OpenAlex 255 FWCI41.677

Pyridine: the scaffolds with significant clinical diversity

review Full Text OpenAlex 194 FWCI6.104

Strengths of Acids in Acetonitrile

article Full Text OpenAlex 157 FWCI12.333

“Magic Chloro”: Profound Effects of the Chlorine Atom in Drug Discovery

review Full Text OpenAlex 139 FWCI5.997

Replacement of Less-Preferred Dipolar Aprotic and Ethereal Solvents in Synthetic Organic Chemistry with More Sustainable Alternatives

review Full Text OpenAlex 128 FWCI3.084

Stereoelectronic power of oxygen in control of chemical reactivity: the anomeric effect is not alone

review Full Text OpenAlex 125 FWCI3.252

Forever young: the first seventy years of ferrocene

review Full Text OpenAlex 107 FWCI3.427

N‐Atom Deletion in Nitrogen Heterocycles

article Full Text OpenAlex 97 FWCI7.516