专题：Chemical Reaction Mechanisms

This cluster of papers explores nucleophilic reactivity in organic chemistry, covering topics such as nucleophilicity scales, acidity scales, phosphate hydrolysis mechanisms, enzymatic mechanisms, superbases for organic synthesis, electrophilicity parameters, aminolysis reactions, transition state analysis, hydride transfer reactions, and their applications in organic synthesis.
最新文献
Messy Chemistry and the Emergence of Life

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The importance of nitrile functionality: FDA-approved small molecules from 2021 to 2024

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Experimental and spectroscopic evidence of the hidden triplet transition state of quinone methide: a new reactivity paradigm

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Myths and Truths About Electrophilic Aromatic Substitution: The Particular Case of Fluorobenzene

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Synthesis, chemical properties and possibility of practical application of s-derivatives of con-densed 1,2,4-triazine-3-thiones

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Toward a unified theory of ATP synthesis/hydrolysis: Integrating physics, chemistry, and biology

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Comment on “Intramolecular Proton-Coupled Hydride Transfers with Relatively Low Activation Barriers”

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Exploring Antiurease Activity of Antibiotics: Insights From In Vitro, SAR, In Silico, DNA Docking, and MD Simulation Studies

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Solvent Sustainability in Drug Discovery: Where Are We Now, and How Can We Improve?

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On the question of the transformation of amino acids into aldimine N-oxides (nitrones): molecular electron density theory (MEDT) considerations

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近5年高被引文献
An Update on the Nitrogen Heterocycle Compositions and Properties of U.S. FDA-Approved Pharmaceuticals (2013–2023)

review Full Text OpenAlex 657 FWCI171.6371

Pyridine: the scaffolds with significant clinical diversity

review Full Text OpenAlex 285 FWCI28.6108

Current Topics on Chemistry and Biochemistry Vol. 1

book Full Text OpenAlex 244 FWCI90.492

“Magic Chloro”: Profound Effects of the Chlorine Atom in Drug Discovery

review Full Text OpenAlex 216 FWCI24.9034

Replacement of Less-Preferred Dipolar Aprotic and Ethereal Solvents in Synthetic Organic Chemistry with More Sustainable Alternatives

review Full Text OpenAlex 169 FWCI17.8893

Forever young: the first seventy years of ferrocene

review Full Text OpenAlex 140 FWCI14.6484

Electrophilicity index revisited

review Full Text OpenAlex 126 FWCI12.3398

Cyrene: a bio-based novel and sustainable solvent for organic synthesis

article Full Text OpenAlex 120 FWCI11.9606

Density functional theory, chemical reactivity, and the Fukui functions

article Full Text OpenAlex 115 FWCI11.357

Electrophilicity and nucleophilicity scales at different DFT computational levels

article Full Text OpenAlex 110 FWCI16.8114