专题:Synthesis and Catalytic Reactions

This cluster of papers focuses on the catalytic C-H amination reactions, including nitrene transfer methods, enantioselective synthesis of aziridines, and the use of sulfoximines in medicinal chemistry. The research covers various metal-catalyzed approaches and their applications in the synthesis of biologically relevant compounds.
最新文献
8-Quinox Cobalt Catalyst Enables the Reductive Alkylative Addition of Sulfinylamines with Unactivated Alkyl Halides

article Full Text OpenAlex

Microwave-enhanced additive-free C–H amination of benzoxazoles catalysed by supported copper

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Synthesis of 6-ethoxyphenyl 4-fluorobenzenesulfonate-tagged thiosemicarbazones as carbonic anhydrase inhibitors: In-vitro and in silico approach

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Late-Stage C–H Functionalization of Nimesulide via (Nimesulide)(3,5-dimethylisoxazol-4-yl)iodonium Salt Formation

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Sustainable synthesis of 1-thiol-3-alkyl bicyclo[1.1.1]pentanes via electron donor–acceptor complex photoactivation: a metal- and additive-free strategy for bioisostere design

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Exploring the SAR of 1,2,3‐Triazoles as Tumor‐Associated Carbonic Anhydrases IX and XII Inhibitors for Anticancer Applications

review Full Text OpenAlex

Structural Optimizations on the Scaffold of 7H‐Pyrrolo[2,3‐d]Pyrimidine to Develop Potent iNOS Inhibitors With Improved Antiarthritis Activity In Vivo

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Comprehensive Insights Into Sulfanilamido‐Based Medicinal Design and Research

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Oxone®-mediated Dakin-like reaction to synthesize hydroxyarenes: an approach using pyrazolo[1,5-a]pyrimidines

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Research Advances in the Synthetic Methodologies of N-Trifluoromethylamides

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近5年高被引文献
Late-stage C–H functionalization offers new opportunities in drug discovery

review Full Text OpenAlex 645 FWCI12.111

C–H activation

article Full Text OpenAlex 466 FWCI38.445

Toolbox for Distal C–H Bond Functionalizations in Organic Molecules

review Full Text OpenAlex 412 FWCI7.932

Transition-Metal-Catalyzed, Coordination-Assisted Functionalization of Nonactivated C(sp3)–H Bonds

review Full Text OpenAlex 395 FWCI7.527

Photocatalytic Late-Stage C–H Functionalization

review Full Text OpenAlex 365 FWCI18.986

Single-atom logic for heterocycle editing

article Full Text OpenAlex 336 FWCI36.452

Arene diversification through distal C(sp 2 )−H functionalization

review Full Text OpenAlex 328 FWCI6.583

Put a ring on it: application of small aliphatic rings in medicinal chemistry

review Full Text OpenAlex 328 FWCI6.224

Skeletal editing through direct nitrogen deletion of secondary amines

article Full Text OpenAlex 282 FWCI20.716

Nitrogen-Centered Radicals in Functionalization of sp2 Systems: Generation, Reactivity, and Applications in Synthesis

review Full Text OpenAlex 272 FWCI8.879