This cluster of papers focuses on the diagnosis and treatment of patent ductus arteriosus (PDA) in preterm infants, with a particular emphasis on the use of indomethacin prophylaxis and ibuprofen treatment. It also explores the association between PDA and neonatal morbidity, the use of echocardiography for assessment, and the impact of ductal closure on outcomes such as bronchopulmonary dysplasia. Additionally, it examines the relationship between PDA and congenital heart disease, including cardiomyopathy.