专题：Quinazolinone synthesis and applications

This cluster of papers focuses on the chemistry, synthesis, and pharmacological properties of quinazoline compounds, including indirubin derivatives. It covers a wide range of topics such as inhibition of protein kinases, antitumor activity, antimicrobial effects, and anti-inflammatory properties.
最新文献
Synthesis, Characterization and Antimicrobial Screening of Some Newly Synthesized Glycosides Derivatives

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Exploiting COX-2 engagement for amplifying anticancer potential of Quinazoline-triazole conjugates with superior EGFR/VEGFR-2 inhibition

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Functionalized Aromatic Sulfones from 1,4‐Benzothiazine‐3‐one‐1,1‐Dioxide: Design, Synthesis, Crystal Structure, and In Silico Evaluation Against SARS‐CoV‐2 Proteins

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The glutamyl-prolyl-tRNA synthetase 1 inhibitor halofuginone exerts synergistic antitumor effects with bortezomib in colon cancer cells

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Evodiamine Enhances Chemosensitivity in Colorectal Cancer by Targeting Ribonucleotide Reductase M2

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Multi-Kinase Inhibition by New Quinazoline–Isatin Hybrids: Design, Synthesis, Biological Evaluation and Mechanistic Studies

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Computational Elucidation of Novel Synthetic Scheme for Dasatinib

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Functionalization of pyrazolo[1,5-a]pyrazine-Schiff bases for assessing liquid crystalline properties and antimicrobial activity

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Towards utilizing the full potential of old – but not outdated – drugs for tuberculosis and nontuberculous mycobacterial disease: A clinical pharmacological perspective

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Feiyiliu mixture promotes non-small cell lung cancer cells apoptosis via inhibits ZDHHC18-mediated AKT1 phosphorylation

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近5年高被引文献
Late-stage diversification of indole skeletons through nitrogen atom insertion

article Full Text OpenAlex 323 FWCI55.19526422

Carbon-to-nitrogen single-atom transmutation of azaarenes

article Full Text OpenAlex 158 FWCI30.47363121

Unified Access to Pyrimidines and Quinazolines Enabled by N–N Cleaving Carbon Atom Insertion

article Full Text OpenAlex 154 FWCI26.479971

Application and synthesis of thiazole ring in clinically approved drugs

review Full Text OpenAlex 146 FWCI28.1591782

Functional Roles of JNK and p38 MAPK Signaling in Nasopharyngeal Carcinoma

review Full Text OpenAlex 145 FWCI17.59888959

Treatment strategies and outcomes for patients with EGFR-mutant non-small cell lung cancer resistant to EGFR tyrosine kinase inhibitors: Focus on novel therapies

review Full Text OpenAlex 133 FWCI27.25149947

The Versatility in the Applications of Dithiocarbamates

review Full Text OpenAlex 121 FWCI20.8056915

Bacteriophage treatment of disseminated cutaneous Mycobacterium chelonae infection

article Full Text OpenAlex 117 FWCI24.8670527

The shikimate pathway: gateway to metabolic diversity

review Full Text OpenAlex 109 FWCI47.48967487

Visible-Light-Induced Chemodivergent Synthesis of Tetracyclic Quinazolinones and 3-Iminoisoindoliones via the Substrate Control Strategy

article Full Text OpenAlex 108 FWCI47.05398978