专题：Quinazolinone synthesis and applications

This cluster of papers focuses on the chemistry, synthesis, and pharmacological properties of quinazoline compounds, including indirubin derivatives. It covers a wide range of topics such as inhibition of protein kinases, antitumor activity, antimicrobial effects, and anti-inflammatory properties.
最新文献
Identification of Rutaecarpine-Pyridinium Quaternary Ammonium Conjugates Exhibiting Dual Mechanisms of Membrane-Targeting and DNA Topo I Inhibition as Potent Antimicrobials against Methicillin-Resistant Staphylococcus aureus

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Design and synthesis of benzimidazolium–chalcone salts with multitarget biological activity: Experimental, computational, and gene expression studies

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Enantio- and Diastereoselective Construction of Quinazolinones with N–N Axial and Point Chirality via NHC Organocatalysis

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A difluorocarbene-triggered annulation/ring expansion cascade via sequential single-atom-insertions: direct assembly of 2-fluoroquinazolinones from azo compounds

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Medicinal attributes of fused/substituted quinazoline derivatives as anticancer agents

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Design, synthesis, and optimization of Honokiol-Piperazine derivatives as lung-enriched agents against MRSA pneumonia infection

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Synthesis of new quinazoline-linked fused imidazole-oxazole conjugates; evaluation of anticancer activity, molecular docking, DFT and ADMET studies

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Self-crosslinked polybenzoxazine anion exchange membranes derived from long-chain alkylamine bis-benzoxazine for efficient electrodialysis desalination

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Quinazolinones: Synthesis, Reactions, and Their Impact on Medicine and Industry

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New quinazolinone-thiazolidinedione hybrids as selective anti-lung cancer agents and promising EGFR inhibitors

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近5年高被引文献
Late-stage diversification of indole skeletons through nitrogen atom insertion

article Full Text OpenAlex 357 FWCI35.2122

Carbon-to-nitrogen single-atom transmutation of azaarenes

article Full Text OpenAlex 185 FWCI26.8124

Unified Access to Pyrimidines and Quinazolines Enabled by N–N Cleaving Carbon Atom Insertion

article Full Text OpenAlex 175 FWCI16.8941

Application and synthesis of thiazole ring in clinically approved drugs

review Full Text OpenAlex 163 FWCI23.554

Functional Roles of JNK and p38 MAPK Signaling in Nasopharyngeal Carcinoma

review Full Text OpenAlex 151 FWCI12.3917

The shikimate pathway: gateway to metabolic diversity

review Full Text OpenAlex 147 FWCI34.6565

Treatment strategies and outcomes for patients with EGFR-mutant non-small cell lung cancer resistant to EGFR tyrosine kinase inhibitors: Focus on novel therapies

review Full Text OpenAlex 145 FWCI20.2576

The Versatility in the Applications of Dithiocarbamates

review Full Text OpenAlex 138 FWCI13.2731

Bacteriophage treatment of disseminated cutaneous Mycobacterium chelonae infection

article Full Text OpenAlex 127 FWCI19.6495

Quinazolinones, the Winning Horse in Drug Discovery

review Full Text OpenAlex 118 FWCI16.9986