专题:Galectins and Cancer Biology

This cluster of papers explores the diverse roles of galectins in immune regulation, inflammation, cancer, macrophage activation, T cell dysfunction, fibrosis, angiogenesis, heart failure, and autoimmunity. Galectins are implicated in modulating various aspects of immune responses and have potential implications for therapeutic interventions in a range of diseases.
最新文献
Targeting ICAM1/ITGB2 with plumbagin preserves intercellular adhesion and attenuates gastric precancerous lesions

article Full Text OpenAlex

High glucose promotes O-GlcNAcylation of ACSL4 to induce ferroptosis of renal tubular epithelial cell

article Full Text OpenAlex

Plasma Galectin-4 and Charcot-Leyden Crystal Protein/Galectin-10 as Emerging Biomarkers of Metabolically Induced Inflammation in Patients with Psoriasis

article Full Text OpenAlex

Hsp60-Bearing Exosomes in Helicobacter pylori-Induced Gastric Tumorigenesis: A Pathomorphological and Therapeutical Overview

review Full Text OpenAlex

Interferon alpha-induced uPAR expression on monocytes as a potential source of increased soluble uPAR in patients with SLE at high risk of developing organ damage

article Full Text OpenAlex

SPP1 high macrophage-induced T-cell stress promotes colon cancer liver metastasis through SPP1/CD44/PI3K/AKT signaling

article Full Text OpenAlex

Deconstruction of tophi and synovium defines SPP1+ macrophages involved in extracellular matrix remodelling in gout

article Full Text OpenAlex

Chemical Probe Approach Reveals Endo-α-mannosidase Triages Misfolded Glycoproteins in the Calnexin/Calreticulin Cycle

article Full Text OpenAlex

Structurally reprogrammed modified citrus pectin (MCP) enables potentiated galectin-3 sequestration and injectable carboxymethyl chitosan/berberine hydrogel construction for osteoarthritis immunotherapy

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Munc13-4 mediates tumor immune evasion by regulating the sorting and secretion of PD-L1 via exosomes

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近5年高被引文献
A Useful Guide to Lectin Binding: Machine-Learning Directed Annotation of 57 Unique Lectin Specificities

article Full Text OpenAlex 328 FWCI40.73589129

Glycosylation: mechanisms, biological functions and clinical implications

review Full Text OpenAlex 247 FWCI118.62106461

The role of galectins in immunity and infection

review Full Text OpenAlex 231 FWCI45.18729022

Protein tyrosine kinase inhibitor resistance in malignant tumors: molecular mechanisms and future perspective

review Full Text OpenAlex 228 FWCI28.18283718

Plant-derived extracellular vesicles: a novel nanomedicine approach with advantages and challenges

review Full Text OpenAlex 227 FWCI27.44442223

PCSK9 promotes the progression and metastasis of colon cancer cells through regulation of EMT and PI3K/AKT signaling in tumor cells and phenotypic polarization of macrophages

article Full Text OpenAlex 216 FWCI25.0357978

MMP9: A Tough Target for Targeted Therapy for Cancer

review Full Text OpenAlex 216 FWCI29.23065091

Targeting galectin-driven regulatory circuits in cancer and fibrosis

review Full Text OpenAlex 201 FWCI38.78737358

Helicobacter pylori and Gastric Cancer: Pathogenetic Mechanisms

review Full Text OpenAlex 193 FWCI97.22097128

Helicobacter pylori: an up-to-date overview on the virulence and pathogenesis mechanisms

article Full Text OpenAlex 185 FWCI55.6352655