专题：Galectins and Cancer Biology

This cluster of papers explores the diverse roles of galectins in immune regulation, inflammation, cancer, macrophage activation, T cell dysfunction, fibrosis, angiogenesis, heart failure, and autoimmunity. Galectins are implicated in modulating various aspects of immune responses and have potential implications for therapeutic interventions in a range of diseases.
最新文献
Glycan-Binding Proteins in Immunity

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Linking FAM111B to metabolic–immune remodeling in breast ductal carcinoma

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Functional analysis of O-GlcNAcylation by networking of OGT interactors and substrates

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The Role of Galectin-3 in Liver Inflammation and Fibrosis

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Endocan as a Novel Biomarker for Endothelial Dysfunction and Cardiovascular Prognosis in ST-Elevation Myocardial Infarction: A Contemporary Literature Review

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Functional immune responses induced by a capsid assembly modulator in chronic hepatitis B virus-infected humanized mice

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Topical Administration of Sitagliptin Prevents Retinal Neurodegeneration in a Model of Glaucoma Induced by Dexamethasone

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Serum CHI3L1 levels correlate with disease activity in rheumatoid arthritis and reveal potential molecular mechanisms

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Galectin-9 activates microglial asparagine endopeptidase and promotes α-synuclein pathology in Parkinson’s disease

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Decoding the CHI3L1/IL-13Rα2 signaling nexus in MASH-fibrosis pathogenesis

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近5年高被引文献
A Useful Guide to Lectin Binding: Machine-Learning Directed Annotation of 57 Unique Lectin Specificities

article Full Text OpenAlex 368 FWCI28.8603

Glycosylation: mechanisms, biological functions and clinical implications

review Full Text OpenAlex 353 FWCI76.6886

The role of galectins in immunity and infection

review Full Text OpenAlex 269 FWCI42.9346

Protein tyrosine kinase inhibitor resistance in malignant tumors: molecular mechanisms and future perspective

review Full Text OpenAlex 250 FWCI20.0206

MMP9: A Tough Target for Targeted Therapy for Cancer

review Full Text OpenAlex 232 FWCI20.8062

Targeting galectin-driven regulatory circuits in cancer and fibrosis

review Full Text OpenAlex 230 FWCI36.3461

Helicobacter pylori and Gastric Cancer: Pathogenetic Mechanisms

review Full Text OpenAlex 220 FWCI66.9729

Glycoconjugates: Synthesis, Functional Studies, and Therapeutic Developments

review Full Text OpenAlex 210 FWCI15.6002

LAG-3, TIM-3, and TIGIT: Distinct functions in immune regulation

review Full Text OpenAlex 201 FWCI44.6574

New insights into fibrosis from the ECM degradation perspective: the macrophage-MMP-ECM interaction

review Full Text OpenAlex 189 FWCI15.701