专题:Enzyme function and inhibition

This cluster of papers explores the role of carbonic anhydrases in medicine and biotechnology, focusing on their inhibitors, activators, and their potential therapeutic applications in cancer therapy and CO2 capture. The papers cover a wide range of topics including tumor hypoxia, drug discovery, enzyme structure and function, and the use of carbonic anhydrases as targets for medicinal chemistry.
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The Concise Guide to PHARMACOLOGY 2023/24: Enzymes

article Full Text OpenAlex 423 FWCI63.5114

Application of microbial-induced carbonate precipitation (MICP) techniques to remove heavy metal in the natural environment: A critical review

review Full Text OpenAlex 161 FWCI20.0576

Chemoselective Covalent Modification of K-Ras(G12R) with a Small Molecule Electrophile

article Full Text OpenAlex 143 FWCI11.7516

Recent advances on anticancer activity of coumarin derivatives

article Full Text OpenAlex 140 FWCI14.6505

Carbonic anhydrase for CO2 capture, conversion and utilization

review Full Text OpenAlex 117 FWCI9.3775

Identification of potent inhibitors of NEK7 protein using a comprehensive computational approach

article Full Text OpenAlex 106 FWCI15.4907

Carbonic anhydrases in metazoan model organisms: molecules, mechanisms, and physiology

review Full Text OpenAlex 105 FWCI8.6808

Carbonic anhydrase to boost CO2 sequestration: Improving carbon capture utilization and storage (CCUS)

review Full Text OpenAlex 105 FWCI8.2487

Cancer Therapeutic Targeting of Hypoxia Induced Carbonic Anhydrase IX: From Bench to Bedside

article Full Text OpenAlex 100 FWCI8.8565

TXNIP: A Double‐Edged Sword in Disease and Therapeutic Outlook

review Full Text OpenAlex 99 FWCI8.2494