专题：Porphyrin Metabolism and Disorders

This cluster of papers explores the molecular mechanisms of heme biosynthesis, including the catalysis by cobalamin-dependent enzymes, genetic mutations leading to porphyrias, microbial production of vitamin B12, and the use of RNA interference therapy and liver transplantation for the treatment of related disorders. It also delves into metabolic engineering and genomic analysis related to heme biosynthesis pathways.
最新文献
Integrated structural dynamics uncover a new B12 photoreceptor activation mode

article Full Text OpenAlex

Vitamin B6 (pyridoxine)

article Full Text OpenAlex

Redox hysteresis controls the NADH-dependent reduction of cytochrome b 5 in rat microsomes

article Full Text OpenAlex

Quantitative Treatments for Explaining the Mechanism and Kinetics of Catalytic Electron Transfers in Murburn Processes, Particularly Involving Heme Enzymes Like (Per)oxidases and P450s

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Pyrazole carboxylic acid borneol esters: Novel neuroprotective agents with rapid, efficient brain penetration for the treatment of ischemic stroke

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Ferrioxalate photocatalysis: A multitasking platform for reductive iron catalysis

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Letter to Editor Reg. Original Article: “Evaluating the Impact of Diagnostic Platform Variability on Immunoassay Results for Vitamins B12 and D”

article Full Text OpenAlex

Discovery of a structurally distinct acetylenase in the biosynthesis of mangotoxin

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Systemic engineering and global regulation enabling high-level bilirubin biosynthesis

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The cobalamin-binding domain of cobalamin-dependent radical S-adenosylmethionine enzymes: Familiarity in unfamiliar places

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近5年高被引文献
Molecular Mechanisms of Iron and Heme Metabolism

review Full Text OpenAlex 267 FWCI39.1314

2.7 Å cryo-EM structure of ex vivo RML prion fibrils

article Full Text OpenAlex 146 FWCI12.0574

Creation from Confusion and Fusion in the Porphyrin World─The Last Three Decades of N-Confused Porphyrinoid Chemistry

review Full Text OpenAlex 116 FWCI8.3932

Vitamin B12 in Foods, Food Supplements, and Medicines—A Review of Its Role and Properties with a Focus on Its Stability

review Full Text OpenAlex 101 FWCI7.9882

Mechanism in Protein Chemistry

book Full Text OpenAlex 98 FWCI2.9097

Nonplanar porphyrins: synthesis, properties, and unique functionalities

review Full Text OpenAlex 97 FWCI6.5936

Oxalate homeostasis

review Full Text OpenAlex 95 FWCI13.0746

Advances in PROTEIN CHEMISTRY ANDSTRUCTURAL BIOLOGY

book-chapter Full Text OpenAlex 91 FWCI43.7428

Oxidative protein folding fidelity and redoxtasis in the endoplasmic reticulum

review Full Text OpenAlex 91 FWCI9.2276

High-level secretory production of leghemoglobin in Pichia pastoris through enhanced globin expression and heme biosynthesis

article Full Text OpenAlex 81 FWCI9.1108