专题:Porphyrin Metabolism and Disorders

This cluster of papers explores the molecular mechanisms of heme biosynthesis, including the catalysis by cobalamin-dependent enzymes, genetic mutations leading to porphyrias, microbial production of vitamin B12, and the use of RNA interference therapy and liver transplantation for the treatment of related disorders. It also delves into metabolic engineering and genomic analysis related to heme biosynthesis pathways.
最新文献
Acute hemolytic anemia and methemoglobinemia in a pediatric oncology patient with G6PD deficiency: a case report

article Full Text OpenAlex

Enantioselective C(sp3)–C(sp3) bond formation by synergistic thiamine-dependent radical biocatalysis and photoredox catalysis

article Full Text OpenAlex

Mineral-facilitated aqueous synthesis of hydrogen cyanide from prebiotically abundant amino acids for chemical evolution

article Full Text OpenAlex

Total Vitamin B12 and Holotranscobalamin: Current Evidence, Limitations, and Clinical Utility

preprint Full Text OpenAlex

Afamelanotide improves quality of life and light tolerance in Austrian erythropoietic protoporphyria patients

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Bifunctional WOx/SiO2 catalysts for hydrogen-free upgrading of B100 and bio-ethylene to SAF and green diesel precursors via olefin metathesis and deoxygenation

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Stress-induced iron-sulfur cluster damage as a conserved trigger of the bacterial stringent response

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Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation

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Novel chemistry and structural perspectives in vitamin B 12 -dependent radical SAM enzymes

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A novel frameshift deletion in SLC25A38 and its role in mitochondrial dysfunction: A case study of sideroblastic anemia in a child from Iran

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近5年高被引文献
Molecular Mechanisms of Iron and Heme Metabolism

review Full Text OpenAlex 281 FWCI39.0301

2.7 Å cryo-EM structure of ex vivo RML prion fibrils

article Full Text OpenAlex 155 FWCI12.0468

Creation from Confusion and Fusion in the Porphyrin World─The Last Three Decades of N-Confused Porphyrinoid Chemistry

review Full Text OpenAlex 119 FWCI8.446

Vitamin B12 in Foods, Food Supplements, and Medicines—A Review of Its Role and Properties with a Focus on Its Stability

review Full Text OpenAlex 104 FWCI7.9736

Nonplanar porphyrins: synthesis, properties, and unique functionalities

review Full Text OpenAlex 101 FWCI6.6361

Oxidative protein folding fidelity and redoxtasis in the endoplasmic reticulum

review Full Text OpenAlex 99 FWCI9.204

Mechanism in Protein Chemistry

book Full Text OpenAlex 98 FWCI2.8397

Oxalate homeostasis

review Full Text OpenAlex 98 FWCI12.9978

Advances in PROTEIN CHEMISTRY ANDSTRUCTURAL BIOLOGY

book-chapter Full Text OpenAlex 91 FWCI43.7428

Vitamin B12—Multifaceted In Vivo Functions and In Vitro Applications

review Full Text OpenAlex 89 FWCI21.4986