专题：Cancer, Lipids, and Metabolism

This cluster of papers explores the role of lipid metabolism, including fatty acid synthesis, cholesterol metabolism, and statin use, in the pathogenesis and progression of cancer. It discusses the metabolic reprogramming of cancer cells, the impact of specific enzymes and receptors such as Fatty Acid Synthase and CD36, and the potential therapeutic implications of targeting lipid metabolism in cancer treatment.
最新文献
Albumin Nanoparticles Co-Loaded with Dual Drugs for Enhanced Ferroptosis-Based Cancer Therapy through Modulating Cholesterol Metabolism

article Full Text OpenAlex

Insulin Resistance at the Crossroads of Metabolic Inflammation, Cardiovascular Disease, Organ Failure and Cancer

article Full Text OpenAlex

The Diverse Roles of Lipid Metabolism Reprogramming in Shaping the Tumor Immune Microenvironment

article Full Text OpenAlex

Adipocyte-derived FABP4 promotes metabolism-associated steatotic liver–induced hepatocellular carcinoma by driving ITGB1-mediated β-catenin activation

article Full Text OpenAlex

Emerging roles of the metabolic regulator 3-hydroxy-3-methylglutaryl coenzyme-CoA reductase in human cancers: From biology to therapeutics

article Full Text OpenAlex

SQLE drives bladder cancer progression by boosting mitochondrial oxidative phosphorylation

article Full Text OpenAlex

Prostate Cancer, Version 3.2026, NCCN Clinical Practice Guidelines In Oncology

article Full Text OpenAlex

Efficacy and Safety of Oral PCSK9 Inhibitor Enlicitide in Adults With Heterozygous Familial Hypercholesterolemia

article Full Text OpenAlex

Targeting ferroptosis and cuproptosis in gastrointestinal cancers: molecular mechanisms, metabolic vulnerabilities, and therapeutic interventions

article Full Text OpenAlex

Harnessing plant-derived natural compounds to target ferroptosis, pyroptosis, immune modulation and renin-angiotensin system in renal cell carcinoma

article Full Text OpenAlex

近5年高被引文献
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications

review Full Text OpenAlex 2672 FWCI380.7226

Hepatocellular carcinoma

review Full Text OpenAlex 2090 FWCI279.0096

Targeting ferroptosis as a vulnerability in cancer

review Full Text OpenAlex 2022 FWCI303.6354

AASLD Practice Guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma

article Full Text OpenAlex 1442 FWCI299.2671

Ferroptosis in cancer therapy: a novel approach to reversing drug resistance

review Full Text OpenAlex 1236 FWCI181.3906

Ferroptosis at the intersection of lipid metabolism and cellular signaling

review Full Text OpenAlex 1162 FWCI160.7124

The cell biology of ferroptosis

review Full Text OpenAlex 964 FWCI416.813

CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4

article Full Text OpenAlex 799 FWCI115.5426

Prostate Cancer Review: Genetics, Diagnosis, Treatment Options, and Alternative Approaches

review Full Text OpenAlex 790 FWCI113.2741

2022 Update on Prostate Cancer Epidemiology and Risk Factors—A Systematic Review

review Full Text OpenAlex 713 FWCI210.5325