专题：Aldose Reductase and Taurine

This cluster of papers explores the cellular response to osmotic stress, with a focus on the role of aldose reductase, taurine, and the aldo-keto reductase superfamily in conditions such as diabetes, inflammation, and oxidative stress. It also delves into the implications for mitochondrial function, neuroprotection, and cardiovascular health.
最新文献
Commentary: Lactylation-related gene AKR1A1 contributes to osteoporosis via metabolic–immune regulation: evidence from multi-omics integration, single-cell transcriptomics, and in vitro validation

article Full Text OpenAlex

In silico computational screening and molecular dynamics analysis unveil Moringa oleifera phytochemicals as a promising PPAR-γ receptor agonist for targeted diabetes management strategies

article Full Text OpenAlex

Antibiotic-Mediated Modulation of the Gut Microbiome Identifies Taurine as a Modulator of Adipocyte Function Through TGR5 Signaling

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Exploration of antidiabetic properties of a xanthene derivative, RH by targeting aldose reductase: In Silico studies

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Thiazolidinedione-based dual inhibitors of α-amylase and aldose reductase: Design, in vitro evaluation, and in vivo hypoglycemic activity

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Phloretin delays the progression of diabetic cataract by inhibiting lens aldose reductase enzyme and oxidative damage: In vitro and ex vivo experimental approaches

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Peripheral Administration of Hypertonic Saline Affects Nutrient Metabolism-related Gene Expression in Chicks

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CB1 Deficiency Protects From LPS-Induced Preterm Birth: The Role of the Decidual Endocannabinoid System

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Cinnamic acid induces neurodevelopmental defects via PPARγ signaling in zebrafish

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β-Alanine Is an Unexploited Neurotransmitter in the Pathogenesis and Treatment of Alzheimer’s Disease

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近5年高被引文献
Redox regulation of the immune response

review Full Text OpenAlex 414 FWCI84.79504199

Taurine deficiency as a driver of aging

article Full Text OpenAlex 345 FWCI94.83988845

Oxidative Stress and NRF2/KEAP1/ARE Pathway in Diabetic Kidney Disease (DKD): New Perspectives

review Full Text OpenAlex 151 FWCI18.58344286

Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells

article Full Text OpenAlex 146 FWCI69.88794167

Polyol pathway and redox balance in diabetes

review Full Text OpenAlex 116 FWCI23.57715802

The lens epithelium as a major determinant in the development, maintenance, and regeneration of the crystalline lens

review Full Text OpenAlex 86 FWCI11.44543169

Synthesis and characterization of novel acyl hydrazones derived from vanillin as potential aldose reductase inhibitors

article Full Text OpenAlex 85 FWCI13.71292965

AKR1C1 Protects Corneal Epithelial Cells Against Oxidative Stress-Mediated Ferroptosis in Dry Eye

article Full Text OpenAlex 81 FWCI16.75219122

Capsaicin ameliorates diabetic retinopathy by inhibiting poldip2-induced oxidative stress

article Full Text OpenAlex 80 FWCI23.37037384

Taurine Supplementation as a Neuroprotective Strategy upon Brain Dysfunction in Metabolic Syndrome and Diabetes

review Full Text OpenAlex 80 FWCI13.059933