专题:Pyrrole Synthesis and Applications

This cluster of papers represents recent advancements in the synthesis of pyrroles, a versatile small molecule with applications in medicinal hetero-aromatics, natural product synthesis, and the development of valuable therapeutic agents. The papers cover various synthetic methods, including multicomponent reactions and catalytic processes, as well as the biological activity and potential applications of pyrrole derivatives.
最新文献
Modern perspectives on covalent and reversible covalent inhibitors: From selectivity to clinical translation

article Full Text OpenAlex

An Overview of the Synthesis of 3,4-Dimethyl-1H-Pyrrole and its Potential Applications

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NiFe2O4@PEG Nanomaterials Mediated Synthesis of Functionalized Pyrroles via a Multi‐Component Reaction under Mild Conditions

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Asymmetric Synthesis and Biological Evaluation of 1,3‐ and 1,4‐Disubstituted Isoquinoline‐Containing Lipoxin A4 Analogues

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A Review on Pyrrole Derivatives in Medicinal Chemistry: From Natural Products to Modern Therapeutics

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Catalyst‐Free (3 + 2) Annulation of Morita–Baylis–Hillman Carbonates With Isoquinolines to Access Functionalized Pyrrolo[2,1‐a]Isoquinolines

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Water Extract of Onion Catalyzed Tandem CN and CC Bond Formation via Enaminone‐Michael Addition‐Intramolecular Cyclization: An Efficient Green Synthesis of Multi‐Substituted Pyrrole Derivatives and Their Antioxidant Activity

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CuCN-Catalyzed Synthesis of 11-R1-5,6-Dihydro-1H-pyrrolo[2,1-b][3]benzazepines from 1-R1-1-Ethynyl-2-vinyl-1,2,3,4-tetrahydroisoquinolines

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Activity of Organic Superbase t‐Bu‐P4/DMSO in C‐Vinylation of Ketones with Acetylenes: A Theoretical Study

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Recent advances in the antimicrobial application of the pyrrolo[2,3-d]pyrimidine scaffold: innovative synthetic strategies, structural diversification, and bioactivity evaluation

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近5年高被引文献
Therapeutic potential of pyrrole and pyrrolidine analogs: an update

review Full Text OpenAlex 137 FWCI4.407

Enaminones as building blocks in drug development: Recent advances in their chemistry, synthesis, and biological properties

article Full Text OpenAlex 99 FWCI7.516

Recent Advancements in Pyrrole Synthesis

article Full Text OpenAlex 91 FWCI7.612

Recent Advances in Reactions Using Enaminone in Water or Aqueous Medium

article Full Text OpenAlex 89 FWCI9.921

Catalytic asymmetric preparation of pyrroloindolines: strategies and applications to total synthesis

review Full Text OpenAlex 87 FWCI1.685

Recent progress in the total synthesis of pyrrole-containing natural products (2011–2020)

article Full Text OpenAlex 83 FWCI6.552

Enantioselective Addition of Pyrazoles to Dienes**

article Full Text OpenAlex 82 FWCI6.745

Recent advances in transition metal-free annulation toward heterocycle diversity based on the C–N bond cleavage of enaminone platform

review Full Text OpenAlex 82 FWCI2.677

Emerging and Re-emerging Warheads for Targeted Covalent Inhibitors: An Update

review Full Text OpenAlex 74 FWCI12.824

Recent Advances in Functionalization of Pyrroles and their Translational Potential

review Full Text OpenAlex 74 FWCI1.483