专题：RNA regulation and disease

This cluster of papers explores the functions and regulation of RNA editing by ADAR deaminases, including its impact on gene regulation, innate immunity, microRNA processing, and the genomic landscape. It covers a wide range of topics such as neurological disorders, cancer, and transcriptome diversity.
最新文献
Endosomal escape: A bottleneck for LNP-mediated therapeutics

article Full Text OpenAlex

Haploinsufficiency of ITSN1 is associated with a substantial increased risk of Parkinson’s disease

article Full Text OpenAlex

Cas12e orthologs evolve variable structural elements to facilitate dsDNA cleavage

article Full Text OpenAlex

Functional anatomy of zinc finger antiviral protein complexes

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Vanin-1-Activated Fluorescent Probe for Real-Time In Vivo Imaging of Inflammatory Responses Across Multiple Tissue Types

article Full Text OpenAlex

Intercellular communication is crucial in the regulation of healthy aging via exosomes

review Full Text OpenAlex

CRISPR-Hybrid: A CRISPR-Mediated Intracellular Directed Evolution Platform for RNA Aptamers

article Full Text OpenAlex

Lipid nanoparticle-mediated intracameral mRNA delivery facilitates gene expression and editing in the anterior chamber of the eye

article Full Text OpenAlex

Curcumin Modulates PTPRZ1 Activity and RNA m6A Modifications in Neuroinflammation‐Associated Microglial Response

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Low-background CRISPR/Cas12a sensing system with circular CRISPR RNA for amplified fluorescent detection of antibody in human serum

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近5年高被引文献
CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis

article Full Text OpenAlex 1426 FWCI110.50424007

Strategies for delivering therapeutics across the blood–brain barrier

review Full Text OpenAlex 955 FWCI64.66399927

Inference of CRISPR Edits from Sanger Trace Data

article Full Text OpenAlex 750 FWCI77.902777

Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins

article Full Text OpenAlex 525 FWCI64.48823878

Neurotoxic reactive astrocytes induce cell death via saturated lipids

article Full Text OpenAlex 519 FWCI53.85097516

Lipids and Lipid Derivatives for RNA Delivery

review Full Text OpenAlex 513 FWCI34.81907653

Prime editing for precise and highly versatile genome manipulation

review Full Text OpenAlex 459 FWCI56.61181267

In vivo base editing rescues Hutchinson–Gilford progeria syndrome in mice

article Full Text OpenAlex 449 FWCI37.74504935

The Machinery of Exosomes: Biogenesis, Release, and Uptake

review Full Text OpenAlex 432 FWCI80.2096161

Mechanism and Applications of CRISPR/Cas-9-Mediated Genome Editing

review Full Text OpenAlex 380 FWCI23.21271769