专题：RNA regulation and disease

This cluster of papers explores the functions and regulation of RNA editing by ADAR deaminases, including its impact on gene regulation, innate immunity, microRNA processing, and the genomic landscape. It covers a wide range of topics such as neurological disorders, cancer, and transcriptome diversity.
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Inference of CRISPR Edits from Sanger Trace Data

article Full Text OpenAlex 845 FWCI54.7059

Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins

article Full Text OpenAlex 636 FWCI96.6284

The Machinery of Exosomes: Biogenesis, Release, and Uptake

review Full Text OpenAlex 601 FWCI82.7585

Prime editing for precise and highly versatile genome manipulation

review Full Text OpenAlex 561 FWCI40.2134

Endosomal escape: A bottleneck for LNP-mediated therapeutics

article Full Text OpenAlex 481 FWCI90.9915

Cuproptosis: Cellular and molecular mechanisms underlying copper-induced cell death

letter Full Text OpenAlex 418 FWCI42.0947

Reshaping endoplasmic reticulum quality control through the unfolded protein response

review Full Text OpenAlex 411 FWCI39.3711

ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis

article Full Text OpenAlex 401 FWCI30.1131

RNA modifications: importance in immune cell biology and related diseases

review Full Text OpenAlex 387 FWCI30.4582

Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer’s disease: a phase 1b, randomized, placebo-controlled trial

article Full Text OpenAlex 319 FWCI51.155