专题：RNA regulation and disease

This cluster of papers explores the functions and regulation of RNA editing by ADAR deaminases, including its impact on gene regulation, innate immunity, microRNA processing, and the genomic landscape. It covers a wide range of topics such as neurological disorders, cancer, and transcriptome diversity.
最新文献
SARS-CoV-2-induced damage to rat cortical neuronal networks ex vivo is mediated by the pro-inflammatory activation of the cGAS-STING pathway

article Full Text OpenAlex

Discovery and engineering of retrons for precise genome editing

article Full Text OpenAlex

Deficiency of Smooth Muscle Adar1 Exacerbates Vascular Remodeling and Pulmonary Hypertension

article Full Text OpenAlex

N1-methylpseudouridine mRNA modification enhances efficiency and specificity of gene overexpression by preventing Prkra-mediated global translation repression

article Full Text OpenAlex

Revealing VNN1: An Emerging and Promising Target for Inflammation and Redox Balance

review Full Text OpenAlex

Co-Conservation of synaptic gene expression and circuitry in collicular neurons

article Full Text OpenAlex

Exosome-Mediated Delivery of a PLD1 Modulator Overcomes Bioavailability Hurdles to Target Synaptopathy in Neurodegenerative Diseases

article Full Text OpenAlex

JAK1 gain-of-function variant causes alopecia areata, atopic dermatitis, and autoimmune thyroid disease

article Full Text OpenAlex

Decreased SNCA expression in whole-blood RNA analysis of Parkinson’s disease adjusting for neutrophils

article Full Text OpenAlex

Gene and RNA Editing: Revolutionary Approaches to Treating Diseases

review Full Text OpenAlex

近5年高被引文献
Inference of CRISPR Edits from Sanger Trace Data

article Full Text OpenAlex 768 FWCI79.62574521

Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins

article Full Text OpenAlex 538 FWCI65.71893036

Prime editing for precise and highly versatile genome manipulation

review Full Text OpenAlex 479 FWCI58.45785004

The Machinery of Exosomes: Biogenesis, Release, and Uptake

review Full Text OpenAlex 460 FWCI85.40838751

Cuproptosis: Cellular and molecular mechanisms underlying copper-induced cell death

letter Full Text OpenAlex 378 FWCI61.24530649

Reshaping endoplasmic reticulum quality control through the unfolded protein response

review Full Text OpenAlex 351 FWCI56.32096104

ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis

article Full Text OpenAlex 349 FWCI42.70499782

RNA modifications: importance in immune cell biology and related diseases

review Full Text OpenAlex 339 FWCI43.07420529

Endosomal escape: A bottleneck for LNP-mediated therapeutics

article Full Text OpenAlex 326 FWCI156.56059539

Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer’s disease: a phase 1b, randomized, placebo-controlled trial

article Full Text OpenAlex 276 FWCI82.70435063