专题：RNA regulation and disease

This cluster of papers explores the functions and regulation of RNA editing by ADAR deaminases, including its impact on gene regulation, innate immunity, microRNA processing, and the genomic landscape. It covers a wide range of topics such as neurological disorders, cancer, and transcriptome diversity.
最新文献
Biallelic variants in the noncoding RNA gene RNU4-2 cause a recessive neurodevelopmental syndrome with distinct white matter changes

article Full Text OpenAlex

LncRNA-splicing factor condensates regulate hypoxia-responsive pre-mRNA processing near nuclear speckles

article Full Text OpenAlex

Connectome-seq: high-throughput mapping of neuronal connectivity at single-synapse resolution via barcode sequencing

article Full Text OpenAlex

mtDNA leakage promotes neuron–glia crosstalk to induce epilepsy by cGAS–STING-driven neuroinflammation and serine metabolic reprogramming

article Full Text OpenAlex

5′UTR Editing of the ribosomal protein UL3Z gene unveils its critical roles in pre-rRNA processing and global mRNA translation dynamics

article Full Text OpenAlex

Coronaviruses reprogram the tRNA epitranscriptome to favor viral protein expression

article Full Text OpenAlex

Toehold-VISTA: a machine learning approach to decipher programmable RNA sensor-target interactions

article Full Text OpenAlex

Next-Generation Plant Gene-Editing Tools Empowered by Artificial Intelligence

book-chapter Full Text OpenAlex

Mechanisms linking cytoplasmic decay of translation-defective mRNA to transcriptional adaptation

article Full Text OpenAlex

ADAR1: a central regulator of dsRNA sensing in host-virus interactions

article Full Text OpenAlex

近5年高被引文献
Inference of CRISPR Edits from Sanger Trace Data

article Full Text OpenAlex 827 FWCI56.594

Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins

article Full Text OpenAlex 604 FWCI100.2989

The Machinery of Exosomes: Biogenesis, Release, and Uptake

review Full Text OpenAlex 569 FWCI83.704

Prime editing for precise and highly versatile genome manipulation

review Full Text OpenAlex 540 FWCI41.5941

Endosomal escape: A bottleneck for LNP-mediated therapeutics

article Full Text OpenAlex 442 FWCI95.2657

Cuproptosis: Cellular and molecular mechanisms underlying copper-induced cell death

letter Full Text OpenAlex 403 FWCI42.9095

Reshaping endoplasmic reticulum quality control through the unfolded protein response

review Full Text OpenAlex 394 FWCI40.3064

ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis

article Full Text OpenAlex 387 FWCI30.1558

RNA modifications: importance in immune cell biology and related diseases

review Full Text OpenAlex 374 FWCI30.507

Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer’s disease: a phase 1b, randomized, placebo-controlled trial

article Full Text OpenAlex 305 FWCI53.0275