专题:RNA regulation and disease

This cluster of papers explores the functions and regulation of RNA editing by ADAR deaminases, including its impact on gene regulation, innate immunity, microRNA processing, and the genomic landscape. It covers a wide range of topics such as neurological disorders, cancer, and transcriptome diversity.
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Inference of CRISPR Edits from Sanger Trace Data

article Full Text OpenAlex 871 FWCI51.2407

Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins

article Full Text OpenAlex 662 FWCI91.458

The Machinery of Exosomes: Biogenesis, Release, and Uptake

article Full Text OpenAlex 641 FWCI58.5733

Prime editing for precise and highly versatile genome manipulation

article Full Text OpenAlex 604 FWCI37.6515

Endosomal escape: A bottleneck for LNP-mediated therapeutics

article Full Text OpenAlex 544 FWCI83.504

Cuproptosis: Cellular and molecular mechanisms underlying copper-induced cell death

article Full Text OpenAlex 434 FWCI40.8182

Reshaping endoplasmic reticulum quality control through the unfolded protein response

article Full Text OpenAlex 434 FWCI37.2266

ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis

article Full Text OpenAlex 423 FWCI27.3968

RNA modifications: importance in immune cell biology and related diseases

article Full Text OpenAlex 403 FWCI27.9119

Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer’s disease: a phase 1b, randomized, placebo-controlled trial

article Full Text OpenAlex 345 FWCI47.948