专题：RNA regulation and disease

This cluster of papers explores the functions and regulation of RNA editing by ADAR deaminases, including its impact on gene regulation, innate immunity, microRNA processing, and the genomic landscape. It covers a wide range of topics such as neurological disorders, cancer, and transcriptome diversity.
最新文献
Mechanisms linking cytoplasmic decay of translation-defective mRNA to transcriptional adaptation

article Full Text OpenAlex

omnideconv: a unifying framework for using and benchmarking single-cell-informed deconvolution of bulk RNA-seq data

article Full Text OpenAlex

Development of an ultra-efficient prime editing system in tomato

article Full Text OpenAlex

ADAR-GPT : A continually fine-tuned language model for predicting A-to-I RNA editing sites

article Full Text OpenAlex

Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology

article Full Text OpenAlex

NAT10 triggers colorectal cancer progression via promoting PPAN-regulated DNA damage repair

article Full Text OpenAlex

RNA-guided STAT3 modification fine tunes the epigenetic and epitranscriptomic regulation of CD4 + T helper cell differentiation during non-small cell lung cancer (NSCLC)

article Full Text OpenAlex

Epitranscriptomic control of cancer hallmarks: Functions, mechanisms, and therapeutics of RNA modifications

article Full Text OpenAlex

Targeting STING to generate therapeutic anti-tumor immunity

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Neurons undergo IFNγ-driven persistent epigenetic shifts and synaptopathy in encephalitis

article Full Text OpenAlex

近5年高被引文献
Inference of CRISPR Edits from Sanger Trace Data

article Full Text OpenAlex 804 FWCI56.6168

Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins

article Full Text OpenAlex 574 FWCI100.132

The Machinery of Exosomes: Biogenesis, Release, and Uptake

review Full Text OpenAlex 515 FWCI80.6002

Prime editing for precise and highly versatile genome manipulation

review Full Text OpenAlex 511 FWCI41.5629

Endosomal escape: A bottleneck for LNP-mediated therapeutics

article Full Text OpenAlex 391 FWCI94.5359

Cuproptosis: Cellular and molecular mechanisms underlying copper-induced cell death

letter Full Text OpenAlex 390 FWCI42.8931

Reshaping endoplasmic reticulum quality control through the unfolded protein response

review Full Text OpenAlex 373 FWCI40.4148

ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis

article Full Text OpenAlex 366 FWCI30.2188

RNA modifications: importance in immune cell biology and related diseases

review Full Text OpenAlex 353 FWCI30.5431

Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer’s disease: a phase 1b, randomized, placebo-controlled trial

article Full Text OpenAlex 291 FWCI52.2351