专题：Signaling Pathways in Disease

This cluster of papers focuses on the role of Calcineurin-NFAT signaling in transcriptional regulation, with a particular emphasis on its involvement in cancer progression, cardiac hypertrophy, and inflammatory responses. The cluster also explores the impact of Prolyl Isomerase Pin1, EMMPRIN/CD147, and immunophilins in modulating this signaling pathway.
最新文献
Reversing cardiac hypertrophy and heart failure using a cardiac targeting peptide linked to miRNA106a

article Full Text OpenAlex

Inhibition of Scarb1 on Endothelial Cells Attenuates Pressure Overload-induced Heart Failure Progression

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Aberrant humoral immune responses and intestinal homeostasis in Cd38 Bst1 double knockout mice

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Identification and expression analysis of NAC family genes in Eleutherococcus senticosus under salt stress

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Myeloid-targeting immunotherapies overcome inhibitory barriers in immune-evasive neuroblastoma

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NFATc1 deficiency in B cells ameliorates atopic dermatitis

article Full Text OpenAlex

GPLD1 Attenuates Heart Failure via Dual Membrane Localization to Inhibit uPAR

article Full Text OpenAlex

Discovery of Orally Efficacious Bridged Piperazines as smTNF Modulators

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FMRP-dependent translational control negatively regulates Adaptor Protein Complex 2-mediated endocytosis

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Protein kinase A: a quirky prototype

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近5年高被引文献
Signaling pathways and targeted therapy for myocardial infarction

review Full Text OpenAlex 557 FWCI19.259

The Rise of Molecular Glues

article Full Text OpenAlex 445 FWCI26.853

Histone Lactylation Boosts Reparative Gene Activation Post–Myocardial Infarction

article Full Text OpenAlex 271 FWCI25.516

Cells of the Immune System in Cardiac Remodeling: Main Players in Resolution of Inflammation and Repair After Myocardial Infarction

review Full Text OpenAlex 240 FWCI10.565

Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2

article Full Text OpenAlex 232 FWCI16.034

No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor

article Full Text OpenAlex 188 FWCI12.92

Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy

article Full Text OpenAlex 178 FWCI11.597

Mitochondrial dysfunction in macrophages promotes inflammation and suppresses repair after myocardial infarction

article Full Text OpenAlex 170 FWCI35.153

Cardiac Resident Macrophage-Derived Legumain Improves Cardiac Repair by Promoting Clearance and Degradation of Apoptotic Cardiomyocytes After Myocardial Infarction

article Full Text OpenAlex 164 FWCI34.513

Integrins as attractive targets for cancer therapeutics

review Full Text OpenAlex 156 FWCI5.146