This cluster of papers focuses on cerebrospinal fluid disorders, including spontaneous spinal cerebrospinal fluid leaks, intracranial hypotension, and chronic subdural hematoma. It explores the pathophysiology, surgical management, risk factors, recurrence predictors, and potential pharmacotherapies for these conditions. Connective tissue disorders and angiogenesis are also highlighted as relevant factors. The cluster encompasses a wide range of research on diagnosis, treatment, and outcomes related to cerebrospinal fluid disorders and hematomas.