This cluster of papers represents current research on Moyamoya disease and syndrome, focusing on genetic susceptibility (RNF213 gene), revascularization surgery, neurological complications, and epidemiological features. It covers a wide range of topics including the clinical features, treatment outcomes, genetic factors, and long-term prognosis of Moyamoya disease. The research also explores the pathophysiology, neurocognitive effects, and vascular development associated with this cerebrovascular disease.