专题：Chromatin Remodeling and Cancer

This cluster of papers focuses on the role of chromatin remodeling, particularly the SWI/SNF complexes and ARID1A mutations, in cancer development and progression. It explores the impact of these mutations on epigenetic regulation, tumor suppression, genomic analysis, oncogenic transformation, and synthetic lethality. Additionally, it delves into the involvement of chromatin remodeling in mammalian development.
最新文献
The chromatin remodeller CHD4 regulates transcription factor binding to both prevent activation of silent enhancers and maintain active regulatory elements

article Full Text OpenAlex

Mode of action of a DCAF16-recruiting targeted glue that can selectively degrade BRD9

article Full Text OpenAlex

Letter to the editor: “Budd-Chiari syndrome from pleomorphic sarcoma compressing the inferior vena cava: A case report”

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Medulloblastoma: Current Standard of Care and Future Treatment Opportunities

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Shifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in dedifferentiated endometrial carcinomas

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Novel SMARCA2 :: DDIT3 Fusion in Primary Subcutaneous Myxoid Liposarcoma due to an Unusual Unbalanced Chromosomal Translocation

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Beyond chromosomes: exploring the diverse functions of extrachromosomal circular DNA

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1083 Alterations in SWI/SNF Complex Subunits and Mismatch Repair Proteins in Undifferentiated/dedifferentiated Uterine Carcinoma: A Case Series from A Single Institution

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1153 Clinicopathologic Spectrum of Salivary Clear Cell Carcinomas with SMARCA2::CREM Fusion. A more aggressive variant?

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1185 The Clinical and Pathological Features of Sinonasal Neuroepithelial and Neuroendocrine Tumors with BRG1 Deficiency

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近5年高被引文献
Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma

article Full Text OpenAlex 578 FWCI216.01732472

Molecular mechanisms of platinum‑based chemotherapy resistance in ovarian cancer (Review)

review Full Text OpenAlex 242 FWCI74.32144835

Updated diagnostic criteria and nomenclature for neurofibromatosis type 2 and schwannomatosis: An international consensus recommendation

article Full Text OpenAlex 241 FWCI39.7321708

Targeted therapy for head and neck cancer: signaling pathways and clinical studies

review Full Text OpenAlex 211 FWCI39.17645601

A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo

article Full Text OpenAlex 190 FWCI23.01393254

The 2021 World Health Organization Classification of Tumors of the Central Nervous System: What Neuroradiologists Need to Know

review Full Text OpenAlex 178 FWCI40.39525284

Generating specificity in genome regulation through transcription factor sensitivity to chromatin

review Full Text OpenAlex 149 FWCI19.3218578

Classification of adult‐type diffuse gliomas: Impact of the World Health Organization 2021 update

review Full Text OpenAlex 138 FWCI30.86378869

Charting co-mutation patterns associated with actionable drivers in intrahepatic cholangiocarcinoma

article Full Text OpenAlex 138 FWCI42.0288147

Single-nucleus chromatin accessibility profiling highlights regulatory mechanisms of coronary artery disease risk

article Full Text OpenAlex 134 FWCI16.36819801