专题：FOXO transcription factor regulation

This cluster of papers focuses on the regulation and diverse functions of FoxO transcription factors, including their roles in cell cycle regulation, response to oxidative stress, metabolism, apoptosis, cancer development and therapy, aging, DNA repair, and insulin signaling.
最新文献
Comment on Santana-Bejarano et al. NRP1 and GFAP Expression in the Medulloblastoma Microenvironment: Implications for Angiogenesis and Tumor Progression. Cancers 2025, 17, 2417

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HDAC1/2-mediated repression of Wnt receptor expression orients asymmetric division polarity in C. elegans .

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A PI3Kδ-Foxo1-FasL signaling amplification loop rewires CD4+ T cell signaling and differentiation

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A systems approach identifies MERTK as a therapeutic vulnerability in ZFTA-RELA-driven ependymomas

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Cellular survivorship bias as a mechanistic driver of muscle stem cell aging

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A first-in-class small-molecule inhibitor targeting AVIL exhibits safety and antitumor efficacy in preclinical models of glioblastoma

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ORGANOSELENIUM COMPOUNDS ACT ON THE GLUCOSE AND LIPID METABOLISM THROUGH DAF-16/FOXO ACTIVATION IN C. elegans

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NRF2: Master regulator of cellular homeostasis and therapeutic vulnerability in cancer

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Disease tolerance and infection pathogenesis age-related tradeoffs in mice

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Chronic TCR signaling-driven suppression of the FOXO1-KLHL6 axis promotes T cell exhaustion

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近5年高被引文献
Efficacy of a Small-Molecule Inhibitor of KrasG12D in Immunocompetent Models of Pancreatic Cancer

article Full Text OpenAlex 335 FWCI33.1793

Coordinating gene expression during the cell cycle

review Full Text OpenAlex 219 FWCI22.9161

FOXO transcription factors as therapeutic targets in human diseases

review Full Text OpenAlex 162 FWCI13.1979

PI3K/AKT signaling pathway as a critical regulator of epithelial-mesenchymal transition in colorectal tumor cells

review Full Text OpenAlex 157 FWCI36.618

Targeting Breast Cancer Stem Cells

review Full Text OpenAlex 155 FWCI30.3206

FOXO transcription factors as mediators of stress adaptation

review Full Text OpenAlex 153 FWCI14.011

Role of p38 MAP kinase in cancer stem cells and metastasis

review Full Text OpenAlex 143 FWCI13.7078

Energy stress modulation of AMPK/FoxO3 signaling inhibits mitochondria-associated ferroptosis

article Full Text OpenAlex 130 FWCI31.495

Transcriptional regulation of EMT transcription factors in cancer

review Full Text OpenAlex 124 FWCI29.0319

Mex3a marks drug-tolerant persister colorectal cancer cells that mediate relapse after chemotherapy

article Full Text OpenAlex 117 FWCI11.4068