专题：FOXO transcription factor regulation

This cluster of papers focuses on the regulation and diverse functions of FoxO transcription factors, including their roles in cell cycle regulation, response to oxidative stress, metabolism, apoptosis, cancer development and therapy, aging, DNA repair, and insulin signaling.
最新文献
Increased WNT10B/FOXO6 signaling promotes cell fate transition in renal tubular cells to aggravate renal inflammation and fibrosis

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Non-canonically regulated heterochronic expression of Hsp70 drives clonal expansion and invasion in Drosophila epithelial tumours

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Sphingosine-1-phosphate induces pulmonary artery smooth muscle cell proliferation, migration and pulmonary arterial remodeling by modulating sonic hedgehog signaling effector FoxM1

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Comment on Santana-Bejarano et al. NRP1 and GFAP Expression in the Medulloblastoma Microenvironment: Implications for Angiogenesis and Tumor Progression. Cancers 2025, 17, 2417

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Distinct molecular pathways regulated by activated AKT and YAP signaling during intrahepatic cholangiocarcinoma progression

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Structural and mechanistic basis of mTORC2 activation of protein kinase AKT/PKB

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Lithium chloride suppresses ferroptosis of induced pluripotent stem cells with ApoE4/E4 from a sporadic Alzheimer's disease patient

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Tumor microenvironment and key signaling pathways in breast cancer progression and therapy resistance: A review

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HDAC1/2-mediated repression of Wnt receptor expression orients asymmetric division polarity in C. elegans

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FOXO1 Integrates Endothelial Hemodynamic, Inflammatory, and Metabolic Pathways in Atherosclerosis

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近5年高被引文献
Coordinating gene expression during the cell cycle

review Full Text OpenAlex 229 FWCI22.7894

IFNα Potentiates Anti–PD-1 Efficacy by Remodeling Glucose Metabolism in the Hepatocellular Carcinoma Microenvironment

article Full Text OpenAlex 197 FWCI19.3548

FOXO transcription factors as mediators of stress adaptation

review Full Text OpenAlex 175 FWCI15.2751

FOXO transcription factors as therapeutic targets in human diseases

review Full Text OpenAlex 171 FWCI13.26

PI3K/AKT signaling pathway as a critical regulator of epithelial-mesenchymal transition in colorectal tumor cells

review Full Text OpenAlex 163 FWCI36.0315

Targeting Breast Cancer Stem Cells

review Full Text OpenAlex 162 FWCI30.2841

Role of p38 MAP kinase in cancer stem cells and metastasis

review Full Text OpenAlex 145 FWCI13.632

Energy stress modulation of AMPK/FoxO3 signaling inhibits mitochondria-associated ferroptosis

article Full Text OpenAlex 137 FWCI32.2716

Cuproptosis related genes associated with Jab1 shapes tumor microenvironment and pharmacological profile in nasopharyngeal carcinoma

article Full Text OpenAlex 137 FWCI18.4424

CircRPN2 Inhibits Aerobic Glycolysis and Metastasis in Hepatocellular Carcinoma

article Full Text OpenAlex 134 FWCI11.4399