专题：Pharmacological Receptor Mechanisms and Effects

This cluster of papers explores the role of sigma receptors, particularly the Sigma-1 receptor, in regulating cellular signaling, calcium signaling, cell survival, and their potential therapeutic implications in neuroprotection, neuropsychiatric disorders, cancer therapy, and neurodegenerative diseases.
最新文献
Piperazine as a privileged scaffold in medicinal chemistry: biological activities, synthetic strategies, and multitarget drug design

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Randomized, double-blind study of zervimesine in mild to moderate Alzheimer's disease

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Alzheimer’s drugs: Lecanemab and donanemab to be reconsidered for NHS after appeal

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The role of oxidative stress-induced damage to nucleic acids in mental disorders

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Dual SARS-COV-2 Mpro and PLpro inhibitors based on an 8-((phenylamino)methyl)-[1,4]dioxinoquinolin-7-one scaffold

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Targeting cholinergic dysfunction and neuroinflammation through rationally designed Thieno[3,2-d]pyrimidine hybrids

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Large scale prospective evaluation of co-folding across 557 Mac1-ligand complexes and three virtual screens

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Developments on BACE 1 Inhibitors as Anti‐Alzheimer Agents: A Perspective on Medicinal Chemistry‐Based Advances

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Prevalence of post-COVID symptoms across variants of concern and follow-up periods: A systematic review and meta-analysis

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Lactate potentiates NMDA receptor currents via an intracellular redox mechanism targeting GluN2B subunits: implications for synaptic plasticity

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近5年高被引文献
6-month consequences of COVID-19 in patients discharged from hospital: a cohort study

article Full Text OpenAlex 887 FWCI106.4394

Persistence of somatic symptoms after COVID-19 in the Netherlands: an observational cohort study

article Full Text OpenAlex 851 FWCI100.566

Mid and long-term neurological and neuropsychiatric manifestations of post-COVID-19 syndrome: A meta-analysis

review Full Text OpenAlex 757 FWCI90.5308

Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients

article Full Text OpenAlex 711 FWCI82.7317

Intramuscular AZD7442 (Tixagevimab–Cilgavimab) for Prevention of Covid-19

article Full Text OpenAlex 662 FWCI64.7286

Prevalence of post-acute COVID-19 syndrome symptoms at different follow-up periods: a systematic review and meta-analysis

review Full Text OpenAlex 542 FWCI64.4019

Efficacy and safety of three new oral antiviral treatment (molnupiravir, fluvoxamine and Paxlovid) for COVID-19：a meta-analysis

review Full Text OpenAlex 437 FWCI43.5557

Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses

review Full Text OpenAlex 403 FWCI39.4227

Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial

article Full Text OpenAlex 402 FWCI38.8187

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

article Full Text OpenAlex 384 FWCI51.4279