专题：Pharmacological Receptor Mechanisms and Effects

This cluster of papers explores the role of sigma receptors, particularly the Sigma-1 receptor, in regulating cellular signaling, calcium signaling, cell survival, and their potential therapeutic implications in neuroprotection, neuropsychiatric disorders, cancer therapy, and neurodegenerative diseases.
最新文献
Decoding Pain: Next‐Generation In Vitro Systems for Mechanistic Insights and Drug Discovery

review Full Text OpenAlex

Alzheimer’s disease: Clinical trials to watch

review Full Text OpenAlex

Correction to “Impact of Exposure to Benzodiazepines on Adverse Effects and Efficacy of PD‐1/PD‐L1 Blockade in Patients With Non‐Small Cell Lung Cancer”

erratum Full Text OpenAlex

Discovery and development of an oral analgesic targeting the α2B adrenoceptor

article Full Text OpenAlex

Main Manuscript for Conserved LIR-specific interaction of Sigma-1 receptor and GABARAP

article Full Text OpenAlex

Dopamine receptor- and noradrenaline transporter-related disruptions are associated with depression and cognitive performance in COVID-19 survivors

article Full Text OpenAlex

Design, Synthesis, and Biological Activity of Novel Para-Substituted N-Cyclopropylmethyl-7α-phenyl-6,14-endoethenotetrahydronorthebaines as Selective Delta Opioid Receptor Agonists

preprint Full Text OpenAlex

Correction: HDAC6 inhibition by ITF3756 modulates PD-L1 expression and monocyte phenotype: insights for a promising immune checkpoint blockade co-treatment therapy

article Full Text OpenAlex

Role of Cannabinoids in Chronic Pain Management: A Pharmacodynamic Perspective

article Full Text OpenAlex

Respiratory and Cardiovascular Activity of LENART01, an Analgesic Dermorphin–Ranatensin Hybrid Peptide, in Anesthetized Rats

article Full Text OpenAlex

近5年高被引文献
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors

article Full Text OpenAlex 468 FWCI79.81

Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: the TOGETHER randomised, platform clinical trial

article Full Text OpenAlex 381 FWCI28.176

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

article Full Text OpenAlex 298 FWCI51.263

GABAA receptors: structure, function, pharmacology, and related disorders

review Full Text OpenAlex 283 FWCI9.242

Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors in clinical trials for cancer immunotherapy

review Full Text OpenAlex 279 FWCI7.128

Association between antidepressant use and reduced risk of intubation or death in hospitalized patients with COVID-19: results from an observational study

review Full Text OpenAlex 239 FWCI8.422

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels

article Full Text OpenAlex 238 FWCI17.59

Randomized Trial of Metformin, Ivermectin, and Fluvoxamine for Covid-19

article Full Text OpenAlex 219 FWCI21.053

A narrative review of molecular mechanism and therapeutic effect of cannabidiol (CBD)

review Full Text OpenAlex 203 FWCI10.32

Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2

article Full Text OpenAlex 201 FWCI14.321