专题:Chemical synthesis and alkaloids

This cluster of papers focuses on the chemistry, pharmacology, synthesis, and biological activities of Amaryllidaceae alkaloids such as galanthamine, narciclasine, and lycorine. These natural compounds show potential as anticancer agents, acetylcholinesterase inhibitors, and have medicinal significance. The research also explores their structure-activity relationships and potential therapeutic applications.
最新文献
Direct evidence for poison use on microlithic arrowheads in Southern Africa at 60,000 years ago

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Engineering an Imine Reductase for Enantioselective Synthesis of Atropisomeric Amides

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Bioinspired Total Syntheses of Skeletally Diverse Lycopodium Alkaloids

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Base-Mediated Annulation Strategy to Naphthol Boronic Ester Derivatives

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Phytochemical Profile, Antioxidant, Anticholinesterase, and Antiproliferative Activities of Endemic Onosma discedens : In Vitro and In Silico Approaches

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Structure-Guided Design of Novel 5-HT 2A Partial Agonists as Psychedelic Analogues with Antidepressant Effects

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Zalsupindole is a Nondissociative, Nonhallucinogenic Neuroplastogen with Therapeutic Effects Comparable to Ketamine and Psychedelics

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Aegeline: A biologically important alkaloid from nature

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Volatile Metabolites in Essential Oil of Ferula violacea

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Isolation, characterization and metabolic profiling of seed endophyte B. licheniformis against Sarocladium oryzae in rice

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近5年高被引文献
Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression

article Full Text OpenAlex 930 FWCI232.86394512

Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder

letter Full Text OpenAlex 575 FWCI144.21400506

Single-Dose Psilocybin Treatment for Major Depressive Disorder

article Full Text OpenAlex 397 FWCI206.90600977

Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors

article Full Text OpenAlex 389 FWCI202.73661915

Efficacy and safety of psilocybin-assisted treatment for major depressive disorder: Prospective 12-month follow-up

article Full Text OpenAlex 380 FWCI95.21660229

Adverse effects of psychedelics: From anecdotes and misinformation to systematic science

review Full Text OpenAlex 292 FWCI73.49610415

Structure-based discovery of nonhallucinogenic psychedelic analogs

article Full Text OpenAlex 282 FWCI70.21277304

Psychedelics reopen the social reward learning critical period

article Full Text OpenAlex 279 FWCI144.88632422

Lysergic Acid Diethylamide–Assisted Therapy in Patients With Anxiety With and Without a Life-Threatening Illness: A Randomized, Double-Blind, Placebo-Controlled Phase II Study

article Full Text OpenAlex 254 FWCI63.64611081

The neural basis of psychedelic action

review Full Text OpenAlex 253 FWCI62.38329115