专题：Cancer-related gene regulation

This cluster of papers focuses on the role of protein arginine methylation, particularly by PRMT1 and PRMT5, in mammals. It explores its involvement in histone methylation, transcriptional regulation, epigenetic control, and its implications in cancer and cell proliferation.
最新文献
Complexoform-restricted covalent TRMT112 ligands that allosterically agonize METTL5

article Full Text OpenAlex

Replication-associated base excision repair/single-strand break repair regulates PARG inhibitor response via the PRMT1/PRMT5/ATR axis

article Full Text OpenAlex

MTAP-Null Tumors: A Comprehensive Review on Synthetic Vulnerabilities and Therapeutic Strategies

article Full Text OpenAlex

Arginine methylation in cancer: mechanisms and therapeutic implications

review Full Text OpenAlex

PRMT3 Drives IDO1-Dependent Radioresistance and Immunosuppression by Promoting Kynurenine Metabolism in Non–Small Cell Lung Cancer

article Full Text OpenAlex

A comprehensive tRNA pseudouridine map uncovers targets dependent on human stand-alone pseudouridine synthases

article Full Text OpenAlex

Tudor-based proteomic strategy pan-specifically enriches and identifies protein arginine methylation

article Full Text OpenAlex

Hypoxia-Induced Histone Lactylation Drives Cisplatin Resistance in Bladder Cancer by Promoting RBM15-Dependent m 6 A Methylation of IGFBP3

article Full Text OpenAlex

YAP/TEAD inhibitor VT3989 in solid tumors: a phase 1/2 trial

article Full Text OpenAlex

Methylation reference datasets from quartet DNA materials for benchmarking epigenome sequencing

article Full Text OpenAlex

近5年高被引文献
Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities

review Full Text OpenAlex 2110 FWCI169.3753

The role of m6A RNA methylation in cancer metabolism

review Full Text OpenAlex 791 FWCI67.2468

Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells

article Full Text OpenAlex 690 FWCI56.3516

Control of protein stability by post-translational modifications

review Full Text OpenAlex 681 FWCI106.9734

A DNA methylation atlas of normal human cell types

article Full Text OpenAlex 573 FWCI93.1477

METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N6-methyladenosine modification of PD-L1 mRNA in breast cancer

article Full Text OpenAlex 485 FWCI40.8687

Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance

review Full Text OpenAlex 480 FWCI39.0466

The Wnt Pathway: From Signaling Mechanisms to Synthetic Modulators

review Full Text OpenAlex 445 FWCI36.4675

FinnGen: Unique genetic insights from combining isolated population and national health register data

preprint Full Text OpenAlex 412 FWCI0

Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer

article Full Text OpenAlex 388 FWCI56.561