专题：Cancer-related gene regulation

This cluster of papers focuses on the role of protein arginine methylation, particularly by PRMT1 and PRMT5, in mammals. It explores its involvement in histone methylation, transcriptional regulation, epigenetic control, and its implications in cancer and cell proliferation.
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Context‐Dependent Chemoselectivity of Aromatic C‐Methyltransferases

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MTAP loss is frequent in oncogene-driven NSCLC and may confer sensitivity to combined PRMT5 inhibitors and targeted therapies

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Claudin proteins as emerging therapeutic targets for solid tumours

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PRMT5 in mitochondria regulates mtDNA stability through TFAM arginine methylation

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Allosteric and energetic remodeling of a PDZ domain by protein domain extensions

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Recruitment of bifunctional regulator thermospermine to methylated ribosomes directs xylem fate

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Role of m⁶A RNA Methylation in Mediating Resistance to Chemotherapy and Immunotherapy in Cancer

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Targeting ENO1 reprograms macrophage polarization to trigger antitumor immunity and improves the therapeutic effect of radiotherapy

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TGF-β in tumor development and progression: mechanisms and therapeutics

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Meta-unstable mRNAs in activated CD8+ T cells are defined by interlinked AU-rich elements and m6A mRNA methylation

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