专题：Cancer-related gene regulation

This cluster of papers focuses on the role of protein arginine methylation, particularly by PRMT1 and PRMT5, in mammals. It explores its involvement in histone methylation, transcriptional regulation, epigenetic control, and its implications in cancer and cell proliferation.
最新文献
Context‐Dependent Chemoselectivity of Aromatic C‐Methyltransferases

article Full Text OpenAlex

Allosteric and energetic remodeling of a PDZ domain by protein domain extensions

article Full Text OpenAlex

Evaluating evidence for UFMylation client diversity

article Full Text OpenAlex

Structural characterization of endogenous microprotein EMBOW reveals an alternative MRT motif for WDR5 ‐interacting site recognition

article Full Text OpenAlex

Role of m⁶A RNA Methylation in Mediating Resistance to Chemotherapy and Immunotherapy in Cancer

article Full Text OpenAlex

UBE2J1 Suppresses Colorectal Cancer Progression via Ubiquitin-Mediated Degradation of RPS3

article Full Text OpenAlex

TGF-β in tumor development and progression: mechanisms and therapeutics

article Full Text OpenAlex

Genetics and environment distinctively shape the human immune cell epigenome

article Full Text OpenAlex

The AHCY–adenosine complex rewires mRNA methylation to enhance fatty acid biosynthesis and tumorigenesis

article Full Text OpenAlex

Polyamine-dependent metabolic shielding regulates alternative splicing

article Full Text OpenAlex

近5年高被引文献
Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities

review Full Text OpenAlex 2195 FWCI169.6066

The role of m6A RNA methylation in cancer metabolism

review Full Text OpenAlex 818 FWCI67.2533

Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells

article Full Text OpenAlex 718 FWCI56.2457

Control of protein stability by post-translational modifications

review Full Text OpenAlex 711 FWCI105.7706

A DNA methylation atlas of normal human cell types

article Full Text OpenAlex 601 FWCI92.9673

Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance

review Full Text OpenAlex 498 FWCI39.0867

The Wnt Pathway: From Signaling Mechanisms to Synthetic Modulators

review Full Text OpenAlex 460 FWCI36.4

FinnGen: Unique genetic insights from combining isolated population and national health register data

preprint Full Text OpenAlex 412 FWCI0

Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer

article Full Text OpenAlex 401 FWCI56.5975

Lactylation of METTL16 promotes cuproptosis via m6A-modification on FDX1 mRNA in gastric cancer

article Full Text OpenAlex 389 FWCI58.0847