Synthesis and Biological Evaluation -- 专题文献

近5年高被引文献

An Update on the Nitrogen Heterocycle Compositions and Properties of U.S. FDA-Approved Pharmaceuticals (2013–2023)

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A review on biological and medicinal impact of heterocyclic compounds

review Full Text OpenAlex 436 FWCI74.6253728

Late-stage diversification of indole skeletons through nitrogen atom insertion

article Full Text OpenAlex 323 FWCI55.19526422

Different Schiff Bases—Structure, Importance and Classification

review Full Text OpenAlex 309 FWCI45.13630263

Nitrogen Containing Heterocycles as Anticancer Agents: A Medicinal Chemistry Perspective

review Full Text OpenAlex 253 FWCI48.79638415

A Fruitful Decade of Organofluorine Chemistry: New Reagents and Reactions

article Full Text OpenAlex 232 FWCI28.19349032

Role of bacterial efflux pumps in antibiotic resistance, virulence, and strategies to discover novel efflux pump inhibitors

review Full Text OpenAlex 218 FWCI37.27595412

Molecular mechanisms governing antifungal drug resistance

review Full Text OpenAlex 205 FWCI57.74330494

Advances and challenges in therapeutic targeting of NRF2

review Full Text OpenAlex 203 FWCI37.69109275

KEAP1‐NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential

review Full Text OpenAlex 188 FWCI23.1370017

专题：Synthesis and Biological Evaluation

最新文献

Current progress of 1,2,3-triazole hybrids as EGFR inhibitors for cancer therapy – a literature review

CD70-Targeting CAR NK Cells Overcome BCMA Downregulation and Improve Survival in High-risk Multiple Myeloma Models

Isoquinoline-Derived Half-Sandwich Ru(II) Arene Complex Potentiates Antitumor Chemoimmunotherapeutic Response

Coumarins as versatile scaffolds: Innovative synthetic strategies for generating diverse heterocyclic libraries in drug discovery

Discovery of Novel Indole Derivatives Containing Imidazolidinone as Potential Antifungal Agents with Mechanistic Studies

Recent advances and application of triazol-5-ylidene (MIC) adducts of the type MIC·E (E = BR ₃ , CS ₂ , CO ₂ , and CSN) and related mesoionic MICX (X = CR ₂ and NR) species

Photoinduced EDA complex triggered difluoroalkylation of quinoxalin-2(1 H )-ones with unactivated alkenes and fluoroalkyl bromides

Thirty years of NRF2: advances and therapeutic challenges

Shikonin Derivative Suppresses Colorectal Cancer Cells Growth via Reactive Oxygen Species‐Mediated Mitochondrial Apoptosis and PI3K/AKT Pathway

Evaluation of Pyrrolone‐Fused Benzosuberene MK2 Inhibitors as Promising Therapeutic Agents for HNSCC: In Vitro Efficacy, In‐Vivo Safety, and Pharmacokinetic Profiling

近5年高被引文献

An Update on the Nitrogen Heterocycle Compositions and Properties of U.S. FDA-Approved Pharmaceuticals (2013–2023)

A review on biological and medicinal impact of heterocyclic compounds

Late-stage diversification of indole skeletons through nitrogen atom insertion

Different Schiff Bases—Structure, Importance and Classification

Nitrogen Containing Heterocycles as Anticancer Agents: A Medicinal Chemistry Perspective

A Fruitful Decade of Organofluorine Chemistry: New Reagents and Reactions

Role of bacterial efflux pumps in antibiotic resistance, virulence, and strategies to discover novel efflux pump inhibitors

Molecular mechanisms governing antifungal drug resistance

Advances and challenges in therapeutic targeting of NRF2

KEAP1‐NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential

专题：Synthesis and Biological Evaluation

最新文献

Current progress of 1,2,3-triazole hybrids as EGFR inhibitors for cancer therapy – a literature review

CD70-Targeting CAR NK Cells Overcome BCMA Downregulation and Improve Survival in High-risk Multiple Myeloma Models

Isoquinoline-Derived Half-Sandwich Ru(II) Arene Complex Potentiates Antitumor Chemoimmunotherapeutic Response

Coumarins as versatile scaffolds: Innovative synthetic strategies for generating diverse heterocyclic libraries in drug discovery

Discovery of Novel Indole Derivatives Containing Imidazolidinone as Potential Antifungal Agents with Mechanistic Studies

Recent advances and application of triazol-5-ylidene (MIC) adducts of the type MIC·E (E = BR 3 , CS 2 , CO 2 , and CSN) and related mesoionic MICX (X = CR 2 and NR) species

Photoinduced EDA complex triggered difluoroalkylation of quinoxalin-2(1 H )-ones with unactivated alkenes and fluoroalkyl bromides

Thirty years of NRF2: advances and therapeutic challenges

Shikonin Derivative Suppresses Colorectal Cancer Cells Growth via Reactive Oxygen Species‐Mediated Mitochondrial Apoptosis and PI3K/AKT Pathway

Evaluation of Pyrrolone‐Fused Benzosuberene MK2 Inhibitors as Promising Therapeutic Agents for HNSCC: In Vitro Efficacy, In‐Vivo Safety, and Pharmacokinetic Profiling

近5年高被引文献

An Update on the Nitrogen Heterocycle Compositions and Properties of U.S. FDA-Approved Pharmaceuticals (2013–2023)

A review on biological and medicinal impact of heterocyclic compounds

Late-stage diversification of indole skeletons through nitrogen atom insertion

Different Schiff Bases—Structure, Importance and Classification

Nitrogen Containing Heterocycles as Anticancer Agents: A Medicinal Chemistry Perspective

A Fruitful Decade of Organofluorine Chemistry: New Reagents and Reactions

Role of bacterial efflux pumps in antibiotic resistance, virulence, and strategies to discover novel efflux pump inhibitors

Molecular mechanisms governing antifungal drug resistance

Advances and challenges in therapeutic targeting of NRF2

KEAP1‐NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential

Recent advances and application of triazol-5-ylidene (MIC) adducts of the type MIC·E (E = BR ₃ , CS ₂ , CO ₂ , and CSN) and related mesoionic MICX (X = CR ₂ and NR) species