专题：Synthesis and Biological Evaluation

This cluster of papers focuses on the synthesis, biological evaluation, and antimicrobial activity of quinoxaline derivatives. It covers a wide range of topics including the development of new catalysts for synthesis, investigation of their biological activities, and their potential as anticancer agents.
最新文献
Unique Bidentate Chelators of Functionalized HeterocyclicFluoroquinolones with Dual Anti-Inflammatory and SelectiveCytotoxic Effects via a C7-C8 Ethylene Diamine Bridge

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DFT investigation of 5,8-diaminoquinoxaline-based alkyl bis-Schiff bases: geometry, spectroscopic analysis, MEP, frontier orbitals, and nonlinear optical characteristics

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QSAR and machine learning applied for the analysis of (fluoro)quinolone activity

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Supporting-electrolyte-free Electrochemical Dechlorinative Benzylation of Quinoxalin-2(1 H )-ones with Benzyl Chlorides

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Current progress of 1,2,3-triazole hybrids as EGFR inhibitors for cancer therapy – a literature review

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Isoquinoline-Derived Half-Sandwich Ru(II) Arene Complex Potentiates Antitumor Chemoimmunotherapeutic Response

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Risk Prediction Model for Development of Heart Failure or Cardiomyopathy After Breast Cancer Treatment

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Indole–Imidazole Hybrids as Emerging Therapeutic Scaffolds: Synthetic Advances and Biomedical Applications

review Full Text OpenAlex

Molecular editing of 3-hydroxyphenyl oxindole derivatives via formal O-insertion and N-insertion: synthesis of dioxolane spirooxindoles and quinoxalin-2(1 H )-ones

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Transition-Metal-Free Base-Promoted Divergent Synthesis of 5-Amide-1,2,3-triazole and 5-Imide-1,2,3-triazole Derivatives

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近5年高被引文献
An Update on the Nitrogen Heterocycle Compositions and Properties of U.S. FDA-Approved Pharmaceuticals (2013–2023)

review Full Text OpenAlex 657 FWCI171.6371

A review on biological and medicinal impact of heterocyclic compounds

review Full Text OpenAlex 490 FWCI47.5112

Late-stage diversification of indole skeletons through nitrogen atom insertion

article Full Text OpenAlex 338 FWCI35.0537

Different Schiff Bases—Structure, Importance and Classification

review Full Text OpenAlex 333 FWCI31.7089

Nitrogen Containing Heterocycles as Anticancer Agents: A Medicinal Chemistry Perspective

review Full Text OpenAlex 282 FWCI43.0984

Role of bacterial efflux pumps in antibiotic resistance, virulence, and strategies to discover novel efflux pump inhibitors

review Full Text OpenAlex 250 FWCI25.6814

A Fruitful Decade of Organofluorine Chemistry: New Reagents and Reactions

article Full Text OpenAlex 242 FWCI19.7934

Molecular mechanisms governing antifungal drug resistance

review Full Text OpenAlex 229 FWCI45.0434

Advances and challenges in therapeutic targeting of NRF2

review Full Text OpenAlex 224 FWCI34.9978

KEAP1‐NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential

review Full Text OpenAlex 205 FWCI16.3079