专题：Synthesis and bioactivity of alkaloids

This cluster of papers focuses on the biochemical, pharmacological, and therapeutic functions of beta-carboline alkaloids such as harmine and cryptolepine. The research covers a wide range of topics including their anticancer, antimalarial, DNA binding, antioxidant, and cytotoxic properties.
最新文献
Recent Advances in Synthesis of Chiral Organoselenium Compounds

article Full Text OpenAlex

Identification of Rutaecarpine-Pyridinium Quaternary Ammonium Conjugates Exhibiting Dual Mechanisms of Membrane-Targeting and DNA Topo I Inhibition as Potent Antimicrobials against Methicillin-Resistant Staphylococcus aureus

article Full Text OpenAlex

Nanoparticle-induced modulation of indole alkaloid biosynthesis and gene expression in Catharanthus roseus in vitro cultures

article Full Text OpenAlex

Antioxidant, Antimicrobial and Antiproliferative Effects of Serjania racemosa Schumach Leaves

article Full Text OpenAlex

Effects of Andrographis paniculata (Burm.f.) Nees,Azadirachta indica A. Juss. and Adhatoda vasica Nees plant extracts on germination, seedling growth and food ingredients in Aflatoxin B1 treated seeds of maize (Zea mays L.)

article Full Text OpenAlex

A systematic review on synthetic utilities of 1,1′-carbonyldiimidazole

article Full Text OpenAlex

Mosquitocidal potential of ricinine from Ricinus communis: An integrative evaluation of larvicidal efficacy, histopathology, non-target toxicity, and in silico mechanism

article Full Text OpenAlex

Medicinal attributes of fused/substituted quinazoline derivatives as anticancer agents

article Full Text OpenAlex

Synthesis of Imidazopyridine- and Indole-Fused Azepinones via an Unusual Friedel–Crafts Alkylation of Chloroacetylated GBB Adducts

article Full Text OpenAlex

Uncoupling DNA binding in solution from cellular efficacy: Structure–distribution relationships of indolo[3,2-b]quinolines in cancer cells

article Full Text OpenAlex

近5年高被引文献
Nano-drug co-delivery system of natural active ingredients and chemotherapy drugs for cancer treatment: a review

review Full Text OpenAlex 261 FWCI17.1039

Anticancer Effects and Mechanisms of Berberine from Medicinal Herbs: An Update Review

review Full Text OpenAlex 167 FWCI23.729

Liposomal irinotecan (Onivyde): Exemplifying the benefits of nanotherapeutic drugs

review Full Text OpenAlex 162 FWCI11.5266

Prospects of Topoisomerase Inhibitors as Promising Anti-Cancer Agents

review Full Text OpenAlex 101 FWCI15.0646

Potential Therapeutic Applications of Plant-Derived Alkaloids against Inflammatory and Neurodegenerative Diseases

review Full Text OpenAlex 94 FWCI14.8741

Milk Thistle (Silybum Marianum L.) as a Novel Multipurpose Crop for Agriculture in Marginal Environments: A Review

review Full Text OpenAlex 89 FWCI14.3019

A Review on Mechanistic Insight of Plant Derived Anticancer Bioactive Phytocompounds and Their Structure Activity Relationship

review Full Text OpenAlex 82 FWCI6.6833

Topoisomerase I inhibitors: Challenges, progress and the road ahead

review Full Text OpenAlex 81 FWCI6.6833

Current development of 1,2,3-triazole derived potential antimalarial scaffolds: Structure- activity relationship (SAR) and bioactive compounds

review Full Text OpenAlex 73 FWCI10.6676

The Effect of Dual Bioactive Compounds Artemisinin and Metformin Co-loaded in PLGA-PEG Nano-particles on Breast Cancer Cell lines: Potential Apoptotic and Anti-proliferative Action

article Full Text OpenAlex 70 FWCI9.9038