专题：Calcium signaling and nucleotide metabolism

This cluster of papers explores the evolution, function, and dysregulation of lysosomal calcium signaling, focusing on the role of two-pore channels, NAADP, TRPML1, and cyclic ADP-ribose in intracellular calcium release and endolysosomal trafficking. It also investigates the implications of these mechanisms in diseases such as mucolipidosis type IV and lysosomal storage disorders.
最新文献
DAMPs and DAMP-sensing receptors in inflammation and diseases

review Full Text OpenAlex

New insight in treating autoimmune diseases by targeting autophagy

review Full Text OpenAlex

Idebenone Antagonizes P53-Mediated Neuronal Oxidative Stress Injury by Regulating CD38-SIRT3 Protein Level

article Full Text OpenAlex

Whole-cell synthesis of nicotinamide mononucleotide by recombinant Saccharomyces cerevisiae from glucose and nicotinamide

article Full Text OpenAlex

ARF6, a component of intercellular bridges, is essential for spermatogenesis in mice

article Full Text OpenAlex

Bafilomycin A1 Molecular Effect on ATPase Activity of Subcellular Fraction of Human Colorectal Cancer and Rat Liver

article Full Text OpenAlex

Coordinated regulation of phosphatidylinositol 4-phosphate and phosphatidylserine levels by Osh4p and Osh5p is an essential regulatory mechanism in autophagy

article Full Text OpenAlex

Impact of Obesity and Lysosomal Dysfunction on Chemoresistance in Ovarian Cancer

article Full Text OpenAlex

Role of CD38 in anti-tumor immunity of small cell lung cancer

article Full Text OpenAlex

Small Peptide Conjugates of Benzothiazole‐2‐Carboxylic Acids Targeting DprE1 Against Tuberculosis

article Full Text OpenAlex

近5年高被引文献
Regulation of SIRT1 and Its Roles in Inflammation

review Full Text OpenAlex 559 FWCI106.11305422

Low-dose metformin targets the lysosomal AMPK pathway through PEN2

article Full Text OpenAlex 512 FWCI64.48823878

Cellular mitophagy: Mechanism, roles in diseases and small molecule pharmacological regulation

review Full Text OpenAlex 464 FWCI163.81723995

Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia

article Full Text OpenAlex 426 FWCI28.16032492

NAD+ metabolism, stemness, the immune response, and cancer

review Full Text OpenAlex 413 FWCI46.93468146

Lysosome biogenesis: Regulation and functions

review Full Text OpenAlex 406 FWCI55.07023732

The emerging mechanisms and functions of microautophagy

review Full Text OpenAlex 392 FWCI90.89075138

Autophagy in tumour immunity and therapy

review Full Text OpenAlex 377 FWCI57.12370379

An overview of autophagy: Mechanism, regulation and research progress

review Full Text OpenAlex 366 FWCI52.45673453

Mitophagy in human health, ageing and disease

review Full Text OpenAlex 355 FWCI125.33431074