专题：Calcium signaling and nucleotide metabolism

This cluster of papers explores the evolution, function, and dysregulation of lysosomal calcium signaling, focusing on the role of two-pore channels, NAADP, TRPML1, and cyclic ADP-ribose in intracellular calcium release and endolysosomal trafficking. It also investigates the implications of these mechanisms in diseases such as mucolipidosis type IV and lysosomal storage disorders.
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Autophagy and autophagy-related pathways in cancer

review Full Text OpenAlex 1415 FWCI76.0338

The mechanisms and roles of selective autophagy in mammals

review Full Text OpenAlex 1025 FWCI42.8506

Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques

article Full Text OpenAlex 631 FWCI67.1651

Autophagy genes in biology and disease

review Full Text OpenAlex 626 FWCI33.6913

TRP (transient receptor potential) ion channel family: structures, biological functions and therapeutic interventions for diseases

article Full Text OpenAlex 525 FWCI78.5411

The emerging mechanisms and functions of microautophagy

review Full Text OpenAlex 468 FWCI21.7567

Autophagy: A Key Regulator of Homeostasis and Disease: An Overview of Molecular Mechanisms and Modulators

article Full Text OpenAlex 425 FWCI44.7141

Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases

review Full Text OpenAlex 403 FWCI41.9273

A phosphoinositide signalling pathway mediates rapid lysosomal repair

article Full Text OpenAlex 373 FWCI30.5219

Calcium homeostasis and cancer: insights from endoplasmic reticulum-centered organelle communications

review Full Text OpenAlex 330 FWCI12.9254