专题：Lipid metabolism and disorders

This cluster of papers focuses on the genetic, pharmacologic, and physiological aspects of lipid metabolism, particularly the role of ANGPTL3, lipoprotein lipase, and related proteins in regulating triglyceride levels and their implications for cardiovascular diseases such as familial chylomicronemia syndrome and atherosclerosis. It also explores the involvement of adipose tissue and metabolic syndrome in lipid regulation.
最新文献
In Vivo Base Editing of PCSK9 with VERVE-102 for Hypercholesterolemia

article Full Text OpenAlex

Familial hypercholesterolaemia in children and adolescents: a European Atherosclerosis Society consensus statement

article Full Text OpenAlex

Oral PCSK9 Inhibitor Enlicitide Versus Oral Nonstatin Therapies

article Full Text OpenAlex

Effect of APOC3 Inhibition With Olezarsen on Coronary Atherosclerosis: Essence-TIMI 73b Imaging Study

article Full Text OpenAlex

Obicetrapib in patients with heterozygous familial hypercholesterolemia: the BROOKLYN randomized clinical trial

article Full Text OpenAlex

Lipoprotein(a)-lowering therapies: a promising future

review Full Text OpenAlex

A Placebo-Controlled Trial of the Oral PCSK9 Inhibitor Enlicitide

article Full Text OpenAlex

Update on familial hypercholesterolemia: An expert clinical consensus from the National Lipid Association

article Full Text OpenAlex

Bempedoic acid directly binds and activates PPARα

article Full Text OpenAlex

Risk-weighted apoB: a novel summary metric outperforming traditional lipid biomarkers in predicting coronary heart disease

article Full Text OpenAlex

近5年高被引文献
Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement

article Full Text OpenAlex 1445 FWCI242.2083

Small Interfering RNA to Reduce Lipoprotein(a) in Cardiovascular Disease

article Full Text OpenAlex 615 FWCI99.9855

Lipid droplet biogenesis and functions in health and disease

review Full Text OpenAlex 597 FWCI14.2003

Molecular mechanisms of metabolic associated fatty liver disease (MAFLD): functional analysis of lipid metabolism pathways

review Full Text OpenAlex 370 FWCI10.9504

2023 Update on European Atherosclerosis Society Consensus Statement on Homozygous Familial Hypercholesterolaemia: new treatments and clinical guidance

article Full Text OpenAlex 363 FWCI97.2572

A focused update to the 2019 NLA scientific statement on use of lipoprotein(a) in clinical practice

review Full Text OpenAlex 340 FWCI38.3613

The Triglyceride/High-Density Lipoprotein Cholesterol (TG/HDL-C) Ratio as a Risk Marker for Metabolic Syndrome and Cardiovascular Disease

review Full Text OpenAlex 327 FWCI11.8846

Long-term efficacy and safety of inclisiran in patients with high cardiovascular risk and elevated LDL cholesterol (ORION-3): results from the 4-year open-label extension of the ORION-1 trial

article Full Text OpenAlex 327 FWCI87.3439

Metabolism of triglyceride-rich lipoproteins in health and dyslipidaemia

review Full Text OpenAlex 314 FWCI12.25

Single Ascending Dose Study of a Short Interfering RNA Targeting Lipoprotein(a) Production in Individuals With Elevated Plasma Lipoprotein(a) Levels

article Full Text OpenAlex 307 FWCI63.4753