专题:Mechanisms of cancer metastasis

This cluster of papers focuses on the molecular mechanisms and functions of metastasis suppressor genes, particularly the NDRG family, in regulating signal transduction, gene expression, cell proliferation, hypoxia response, epithelial-mesenchymal transition, and apoptosis in the context of cancer metastasis.
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ARID1A terminates gastric regeneration to prevent cancer

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Enrichment of SMARCA4 mutations in lung carcinomas presenting as cancer of unknown primary

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Bile Salts and Bacterial Bile Salt Hydrolase Activity Influence Escherichia coli Colonization and FXR Signaling in Colorectal Cancer Organoids

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NF1 loss in estrogen receptor-positive breast cancer induces osteoclast formation and immunosuppression to promote bone metastasis

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YL205, a novel anti-Napi2b antibody drug conjugate (ADC), in patients with ovarian cancer: Preliminary result from a first-in-human trial.

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Curative metastasectomy in a patient with colon cancer harboring BRAF V600E mutation and mismatch repair deficiency – a case study.

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NDRG2 orchestrates circadian clock stability to suppress tumorigenesis and potentiate oxaliplatin response in colorectal cancer

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Chinese guidelines for the diagnosis and comprehensive treatment of colorectal liver metastasis (2025 Edition)

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PLSCR1 drives chemoresistance in TNBC via METTL3/IGF2BP3-mediated mRNA stabilization and EGFR-MAPK pathway activation

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Olink Proteomic Research in Colorectal Cancer: Redefining Minimally Invasive Surgery through Biomarker-driven Insights

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