专题：Phenothiazines and Benzothiazines Synthesis and Activities

This cluster of papers focuses on the biological activities, synthesis, and potential applications of phenothiazines and related compounds. It covers a wide range of topics including antimicrobial, anticancer, and neuroprotective properties, as well as the use of non-antibiotic drugs and the Smiles rearrangement in their synthesis. The cluster also explores the inhibition of DNA synthesis, antioxidant activity, and the potential role of phenothiazines in managing antibiotic-resistant infections.
最新文献
Deciphering mechanistic and therapeutic insight of pyrazolopyrimidines into MRSA suppression: comprehensive in vitro and in vivo study

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Synthesis and In Vitro Screening of Methicillin‐Resistant Staphylococcus aureus Inhibitory Activity of New Bis(benzimidazole‐1,3,4‐oxadiazole) Hybrids Linked by Different Spacers

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Synthesis of 2-Thioxo-1,3-benzothiazin-4-one by PPh 3 -Promoted Desulfurative [4 + 2] Annulation

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The power of resistance: mechanisms of antimicrobial resistance in Mycobacterium tuberculosis and its impact on tuberculosis management

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Development of 6-methyl-4,5-dihydropyrazolo[3,4-d]pyrimidin-4-one derivatives as lead sigma-1 receptor inhibitor: synthesis and biological evaluation via MSI

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Photoexcited Nitroarene-Mediated Oxidation Enables the Total Synthesis of (−)-Securingine G

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Design, Synthesis, Antimicrobial Activity and Molecular Docking of New 1,2,4-Triazepine, 1,3,4,6-Oxatriazepine and Pyridazino[1,2-a] Pyrimidine Derivatives

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A novel antituberculosis agent exhibits potent clinical efficacy and good safety profile: an open-label, randomized-controlled, multicenter, phase 2a trial

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Targeting microbial β-CAs: bridging in silico screening with in vitro validation

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Catalytic Synthesis of Versatile Chiral Heterocycles: En Route to γ-Amino Acid Derivatives

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近5年高被引文献
Antibiotic resistance: The challenges and some emerging strategies for tackling a global menace

review Full Text OpenAlex 866 FWCI58.8211

Late-stage diversification of indole skeletons through nitrogen atom insertion

article Full Text OpenAlex 338 FWCI35.0537

Improved Solubility and Dissolution Rate of Ketoprofen by the Formation of Multicomponent Crystals with Tromethamine

article Full Text OpenAlex 254 FWCI18.8088

Role of bacterial efflux pumps in antibiotic resistance, virulence, and strategies to discover novel efflux pump inhibitors

review Full Text OpenAlex 250 FWCI25.6814

Analysis of the Clinical Pipeline of Treatments for Drug-Resistant Bacterial Infections: Despite Progress, More Action Is Needed

article Full Text OpenAlex 228 FWCI22.2548

Design and synthesis of hybrid compounds as novel drugs and medicines

review Full Text OpenAlex 172 FWCI13.8924

Structural modification aimed for improving solubility of lead compounds in early phase drug discovery

review Full Text OpenAlex 160 FWCI22.4046

The Role of Five-Membered Heterocycles in the Molecular Structure of Antibacterial Drugs Used in Therapy

review Full Text OpenAlex 143 FWCI22.3423

Quaternary Ammonium Salts: Insights into Synthesis and New Directions in Antibacterial Applications

review Full Text OpenAlex 142 FWCI21.8549

Antibiotic Adjuvants: A Versatile Approach to Combat Antibiotic Resistance

review Full Text OpenAlex 140 FWCI13.787