专题：Phenothiazines and Benzothiazines Synthesis and Activities

This cluster of papers focuses on the biological activities, synthesis, and potential applications of phenothiazines and related compounds. It covers a wide range of topics including antimicrobial, anticancer, and neuroprotective properties, as well as the use of non-antibiotic drugs and the Smiles rearrangement in their synthesis. The cluster also explores the inhibition of DNA synthesis, antioxidant activity, and the potential role of phenothiazines in managing antibiotic-resistant infections.
最新文献
Synergistic Potential of Repurposing non-β-lactam Compounds as Class A serine β-lactamases Inhibitor: Insights from MolecularDocking, Molecular Dynamics Simulations and Antimicrobial Potentiation

article Full Text OpenAlex

Delayed-Type Hypersensitivity to Mycobacterium tuberculosis Antigens: The Immunological Mechanism and Potential Therapeutic Strategies—A Systematic Review

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Thyme and cinnamon essential oils inhibit multidrug resistant Escherichia coli and Klebsiella pneumoniae and alter virulence transcripts

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Novel isatin-chalcone molecular hybrids endowed with potent antistaphylococcal properties: In vitro and mechanistic insights

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Five, six and/or seven-membered rings endowed with isoxazole moiety: synthesis, antimicrobial assessment and in silico molecular docking studies

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Maltose-Conjugated Thiosemicarbazones from Substituted Benzaldehydes: Synthesis and Inhibitory Activity against Gram-(+) and Gram-(−) Bacteria

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AI‐Driven Optimization of Cetirizine‐Derived Ligands Targeting Histamine H1 and H2 Receptors: A Computational Drug Design Study

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Deciphering mechanistic and therapeutic insight of pyrazolopyrimidines into MRSA suppression: comprehensive in vitro and in vivo study

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Rongalite as the C1 synthon to assemble 2,3-dihydrobenzothiazin-4-ones and benzo[ d ][1,3]oxathiin-4-ones

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Novel triphenylphosphonium-hydrazone salts: integrated experimental and computational insights into AChE inhibition and resistance-overcoming antimicrobial and antibiofilm potential

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近5年高被引文献
Late-stage diversification of indole skeletons through nitrogen atom insertion

article Full Text OpenAlex 359 FWCI35.2118

Role of bacterial efflux pumps in antibiotic resistance, virulence, and strategies to discover novel efflux pump inhibitors

review Full Text OpenAlex 285 FWCI27.3133

Improved Solubility and Dissolution Rate of Ketoprofen by the Formation of Multicomponent Crystals with Tromethamine

article Full Text OpenAlex 254 FWCI19.1469

Analysis of the Clinical Pipeline of Treatments for Drug-Resistant Bacterial Infections: Despite Progress, More Action Is Needed

article Full Text OpenAlex 236 FWCI22.1816

Design and synthesis of hybrid compounds as novel drugs and medicines

review Full Text OpenAlex 184 FWCI13.8668

Structural modification aimed for improving solubility of lead compounds in early phase drug discovery

review Full Text OpenAlex 166 FWCI22.48

The Role of Five-Membered Heterocycles in the Molecular Structure of Antibacterial Drugs Used in Therapy

review Full Text OpenAlex 164 FWCI24.156

Quaternary Ammonium Salts: Insights into Synthesis and New Directions in Antibacterial Applications

review Full Text OpenAlex 154 FWCI22.2788

Antibiotic Adjuvants: A Versatile Approach to Combat Antibiotic Resistance

review Full Text OpenAlex 144 FWCI13.2188

A Review on The Medicinal And Industrial Applications of N-Containing Heterocycles

review Full Text OpenAlex 138 FWCI11.9575