专题:Synthesis of β-Lactam Compounds

This cluster of papers focuses on the synthesis, stereocontrolled synthesis, and applications of ß-lactams, including their use as building blocks for various biologically active compounds such as anticancer agents and cholesterol absorption inhibitors. The research also delves into asymmetric catalysis, enantioselective synthesis, and the Kinugasa reaction for the production of these versatile compounds.
最新文献
Structural and Kinetic Basis for the Rational Design of Next-Generation β-Lactamase Inhibitors

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Microwave-Assisted Iodine-Catalyzed Diastereomeric Synthesis of3-Pyrrole Substituted β-Lactams

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Exploring the frontiers of penicillin pharmaceuticals: a comprehensive review of advancements and innovations

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Exploring the Synthesis of Peptide Activated Serine Acylating Agents with Enhanced Lactamase Stability: Novel Surrogate β-Lactam Antibiotic-Peptide Hybrids

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Synthesis of new compounds containing β-lactam ring, derived from 4-methoxyaniline and study their antibacterial activity

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Synthesis and antibacterial study of some novel β-lactam derivatives via imine intermediates

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Photochemical Synthesis of 1,2-Diazepine-Fused β-Lactams via Staudinger-Type [2 + 2] Cyclization

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Repurposed β-lactam compounds as EAAT2 allosteric enhancers: An integrated virtual screening, docking, MD simulation, and ADMET study

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Studies on Metastable Heterocycles: 2-Formyl-3-methylene-1-pyrroline

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Design and Synthesis of Benzylidene Phenylacetamide-based Derivatives as Potential Antibacterial Agents Targeting Staphylococcus Aureus Thymidylate Kinase

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近5年高被引文献
Nitrogen Containing Heterocycles as Anticancer Agents: A Medicinal Chemistry Perspective

review Full Text OpenAlex 282 FWCI43.0984

A review: FDA-approved fluorine-containing small molecules from 2015 to 2022

review Full Text OpenAlex 109 FWCI12.5248

Design and synthesis of thiazolidine-2,4-diones hybrids with 1,2-dihydroquinolones and 2-oxindoles as potential VEGFR-2 inhibitors: in-vitro anticancer evaluation and in-silico studies

article Full Text OpenAlex 94 FWCI10.1139

Indole-containing pharmaceuticals: targets, pharmacological activities, and SAR studies

review Full Text OpenAlex 92 FWCI22.6219

CYP2C19 Genetic Testing for Oral P2Y12 Inhibitor Therapy: A Scientific Statement From the American Heart Association

review Full Text OpenAlex 84 FWCI35.3534

Heterocyclic pyrimidine derivatives as promising antibacterial agents

review Full Text OpenAlex 74 FWCI11.2974

2-Oxabicyclo[2.2.2]octane as a new bioisostere of the phenyl ring

article Full Text OpenAlex 53 FWCI8.0683

Complexes of β-lactam antibiotics and their Schiff-base derivatives as a weapon in the fight against bacterial resistance

article Full Text OpenAlex 50 FWCI7.6334

Celecoxib-Loaded Solid Lipid Nanoparticles for Colon Delivery: Formulation Optimization and In Vitro Assessment of Anti-Cancer Activity

article Full Text OpenAlex 48 FWCI4.0543

Fifty years with aspirin and platelets

review Full Text OpenAlex 46 FWCI8.252