专题:Synthesis of β-Lactam Compounds

This cluster of papers focuses on the synthesis, stereocontrolled synthesis, and applications of ß-lactams, including their use as building blocks for various biologically active compounds such as anticancer agents and cholesterol absorption inhibitors. The research also delves into asymmetric catalysis, enantioselective synthesis, and the Kinugasa reaction for the production of these versatile compounds.
最新文献
Synthesis of azetidines by addition of amines to alkenes and alkynes

book-chapter Full Text OpenAlex

Review for "Recent Breakthroughs in Ring-Opening Annulation Reactions of Aziridines"

peer-review Full Text OpenAlex

The Combination of a Novel Pleuromutilin Derivative and Polymyxin B Nonapeptide: An Example of Converting Pleuromutilin from Gram-Positive-Only to Broad-Spectrum

preprint Full Text OpenAlex

OBTAINING INDUCED MUTANTS OF STREPTOMYCEA SPP. WITH INCREASED ANTIBIOTIC ACTIVITY

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Novel Bis-spiro-β-lactams Derived from Some Quinolinones via the Staudinger Synthesis

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Synthesis of Diketopiperazines from α-Amino Amides and Diazophosphonate Ester Using Cp*Rh(III) Catalyst

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Strain-Release of Azetidines for the Synthesis of 3,4,5-Trisubstituted Piperidines

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Pregabalin Combined with Celecoxib in comparison to Celecoxib Alone as Preemptive Analgesia for Patients Undergoing Hip or Knee Arthroplasty

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A Concise overview of diverse analytical techniques for ezetimibe estimation

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Design and synthesis of novel antibacterial agents that targets the bacterial fatty acid pathway

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近5年高被引文献
Nitrogen Containing Heterocycles as Anticancer Agents: A Medicinal Chemistry Perspective

review Full Text OpenAlex 242 FWCI46.67480223

Recent advances in the synthesis and reactivity of azetidines: strain-driven character of the four-membered heterocycle

review Full Text OpenAlex 117 FWCI9.95145571

A review: FDA-approved fluorine-containing small molecules from 2015 to 2022

review Full Text OpenAlex 96 FWCI17.59320641

Design and synthesis of thiazolidine-2,4-diones hybrids with 1,2-dihydroquinolones and 2-oxindoles as potential VEGFR-2 inhibitors: in-vitro anticancer evaluation and in-silico studies

article Full Text OpenAlex 91 FWCI15.64725559

Medicinal chemistry perspectives of 1,2,3,4-tetrahydroisoquinoline analogs – biological activities and SAR studies

review Full Text OpenAlex 88 FWCI6.61959075

Discovery of new anticancer thiourea-azetidine hybrids: design, synthesis, in vitro antiproliferative, SAR, in silico molecular docking against VEGFR-2, ADMET, toxicity, and DFT studies

article Full Text OpenAlex 77 FWCI9.15533925

Indole-containing pharmaceuticals: targets, pharmacological activities, and SAR studies

review Full Text OpenAlex 76 FWCI36.49878911

Azetidines of pharmacological interest

review Full Text OpenAlex 76 FWCI5.30744305

Heterocyclic pyrimidine derivatives as promising antibacterial agents

review Full Text OpenAlex 66 FWCI12.72949152

Modular Synthesis of α‐Quaternary Chiral β‐Lactams by a Synergistic Copper/Palladium‐Catalyzed Multicomponent Reaction

article Full Text OpenAlex 65 FWCI7.29773419