专题：Apelin-related biomedical research

This cluster of papers explores the role of apelin, a novel adipokine, and its receptor APJ in various physiological processes such as cardiovascular regulation, angiogenesis, obesity, diabetes, and neuroprotection. The research covers molecular properties, tissue distribution, signaling pathways, therapeutic potential, and pathophysiological implications of the apelin/APJ system.
最新文献
ELABELA Protects Against Thoracic Aortic Dissection by Maintaining Vascular Smooth Muscle Cells Homeostasis and Regulating NETosis

article Full Text OpenAlex

Metformin: An emerging therapeutic approach for prevention and treatment of preeclampsia

article Full Text OpenAlex

ESM1 SUMOylation mediates bevacizumab resistance in ovarian cancer through ITGB1-FAK-driven angiogenesis

article Full Text OpenAlex

Effect of Maternal Hyperglycemia on Cortical Neuronal Migration: Hypofunction of Reelin Signaling

article Full Text OpenAlex

Apelin-13 confers Neuropeptide Y–mediated neuroprotection and preserves learning and allocentric memory in D-glutamic acid-induced excitotoxicity in rats

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The Discovery of RGH-706, a Highly Efficacious MCH1 Receptor Antagonist, for the Treatment of Obesity and Insatiable Hunger

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The Adipokine Axis in Heart Failure: Linking Obesity, Sarcopenia and Cardiac Dysfunction in HFpEF

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Neuropeptides and the Autonomic Nervous System in Prader–Willi Syndrome

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miRNA regulatory networks as precision diagnostic and therapeutic targets in pulmonary arterial hypertension: from molecular cascades to clinical translation

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Clinical and Molecular Differences of Hypertensive Disorders During Pregnancy

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近5年高被引文献
Inflammation in obesity, diabetes, and related disorders

review Full Text OpenAlex 1830 FWCI266.1993

What is the pipeline for future medications for obesity?

review Full Text OpenAlex 275 FWCI95.7272

Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS)

article Full Text OpenAlex 268 FWCI38.197

Estimated Lifetime Cardiovascular, Kidney, and Mortality Benefits of Combination Treatment With SGLT2 Inhibitors, GLP-1 Receptor Agonists, and Nonsteroidal MRA Compared With Conventional Care in Patients With Type 2 Diabetes and Albuminuria

article Full Text OpenAlex 266 FWCI52.8117

Diabetic Nephropathy: Update on Pillars of Therapy Slowing Progression

review Full Text OpenAlex 242 FWCI48.4508

Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling

article Full Text OpenAlex 241 FWCI41.3148

A systems view of the vascular endothelium in health and disease

review Full Text OpenAlex 229 FWCI100.0646

The neuroprotective effects of glucagon-like peptide 1 in Alzheimer’s and Parkinson’s disease: An in-depth review

review Full Text OpenAlex 204 FWCI25.633

Signaling pathways in vascular function and hypertension: molecular mechanisms and therapeutic interventions

review Full Text OpenAlex 198 FWCI39.3632

Endothelial Cell Dysfunction and Increased Cardiovascular Risk in Patients With Chronic Kidney Disease

review Full Text OpenAlex 189 FWCI40.9361