专题：Apelin-related biomedical research

This cluster of papers explores the role of apelin, a novel adipokine, and its receptor APJ in various physiological processes such as cardiovascular regulation, angiogenesis, obesity, diabetes, and neuroprotection. The research covers molecular properties, tissue distribution, signaling pathways, therapeutic potential, and pathophysiological implications of the apelin/APJ system.
最新文献
Therapeutic Potential of Factor Xa and Thrombin Inhibitors in Preserving Pancreatic Islets' Function in Experimental Diabetic Mice

article Full Text OpenAlex

Emodin Alleviates Acute Pancreatitis‐Associated Acute Lung Injury by Inhibiting Serum Exosomal miRNA‐21‐3p‐Induced M1 Alveolar Macrophage Polarisation

article Full Text OpenAlex

Excess GDNF associates with a subtype of schizophrenia with enhanced dopamine and increased prefrontal dysfunction

preprint Full Text OpenAlex

[Expression of Concern] Apelin‑13 induces autophagy in hepatoma HepG2 cells through ERK1/2 signaling pathway‑dependent upregulation of Beclin1

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Angiotensin Converting Enzyme 2 (ACE2) G8790A Gene Polymorphism as a Risk Factor for Essential Hypertension

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Novel small molecule analogs for advancing Apelin receptor antagonism with enhanced plasma and microsomal stability

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High Plasma Renin and Aldosterone Levels Are Associated With a Unique Phenotype in Primary Hypertension

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Astaxanthin-rich Nannochloropsis oculata mitigates high-fat diet-induced liver dysfunction in zebrafish by modulating lipid metabolism and oxidative stress

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Beyond Blood Pressure: Emerging Pathways and Precision Approaches in Hypertension-Induced Kidney Damage

review Full Text OpenAlex

Cardiorenal Syndrome: Molecular Pathways Linking Cardiovascular Dysfunction and Chronic Kidney Disease Progression

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近5年高被引文献
Inflammation in obesity, diabetes, and related disorders

review Full Text OpenAlex 1331 FWCI69.245

Fibrosis in Chronic Kidney Disease: Pathogenesis and Consequences

review Full Text OpenAlex 265 FWCI8.975

Mechanistic insights and perspectives involved in neuroprotective action of quercetin

review Full Text OpenAlex 228 FWCI6.379

Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS)

article Full Text OpenAlex 221 FWCI41.659

Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling

article Full Text OpenAlex 199 FWCI32.613

Neuroprotective Effect of SGLT2 Inhibitors

review Full Text OpenAlex 197 FWCI6.457

GLP-1 receptor agonists (GLP-1RAs): cardiovascular actions and therapeutic potential

review Full Text OpenAlex 180 FWCI5.846

What is the pipeline for future medications for obesity?

review Full Text OpenAlex 165 FWCI41.645

Salidroside: A review of its recent advances in synthetic pathways and pharmacological properties

review Full Text OpenAlex 158 FWCI3.748

Diabetic Nephropathy: Update on Pillars of Therapy Slowing Progression

review Full Text OpenAlex 151 FWCI12.193