专题:14-3-3 protein interactions

This cluster of papers focuses on the structure, function, and regulation of 14-3-3 proteins, which play diverse roles in cell signaling, cancer development, phosphorylation-mediated processes, protein-protein interactions, apoptosis regulation, neurological disorders, cell cycle control, and act as molecular chaperones involved in protein stabilization.
最新文献
A CK2-FBXW11 kinase-E3 ubiquitin ligase cascade is a metabolic sensor regulating Tryptophan 2,3-dioxygenase stability

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Exploring the characteristics of the SKP2-CDK6 axis in pancreatic cancer cell metastasis and its clinical significance

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A systematic review on efficient and scalable algorithms for finding protein complexes in protein-protein interaction networks

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Microscopy-based bead protein–protein interaction assay v1

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Benchmarking co-folding methods to predict the structures of covalent protein–ligand complexes

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Neuroligin family genes expression associated with first-line treatment outcomes in patients (pts) with metastatic colorectal cancer (mCRC): Data from CALGB/SWOG 80405 (Alliance).

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Efficacy and safety of Cadonilimab in the treatment of recurrent/metastatic and advanced cervical cancer: a systematic review and meta-analysis

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Identification of SHC2 as a prognostic biomarker: from pan-cancer analysis to colon adenocarcinoma validation

preprint Full Text OpenAlex

Discovery of Dimer-Dependent Aminoacrylamide Molecular Glues for 14–3–3 Protein–Protein Interactions

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The Compatibility of the Epichloë bromicola–Hordeum Association

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近5年高被引文献
BindingDB Entry 50022499: ZD1839 (Iressa): an orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy.

article Full Text OpenAlex 933 FWCI0

Resilience to autosomal dominant Alzheimer’s disease in a Reelin-COLBOS heterozygous man

article Full Text OpenAlex 169 FWCI50.5746029

Structural insights into the BRAF monomer-to-dimer transition mediated by RAS binding

article Full Text OpenAlex 131 FWCI15.87592138

PROTAC-DB 2.0: an updated database of PROTACs

article Full Text OpenAlex 125 FWCI15.26057559

Structural insights into the functional roles of 14-3-3 proteins

review Full Text OpenAlex 105 FWCI12.79919243

SRC kinase-mediated signaling pathways and targeted therapies in breast cancer

review Full Text OpenAlex 100 FWCI15.83516876

New insights into protein–protein interaction modulators in drug discovery and therapeutic advance

review Full Text OpenAlex 93 FWCI44.66299194

Patient-specific Boolean models of signalling networks guide personalised treatments

article Full Text OpenAlex 93 FWCI26.33477636

The Tubulin Code, from Molecules to Health and Disease

review Full Text OpenAlex 85 FWCI20.80039329

RAF-like protein kinases mediate a deeply conserved, rapid auxin response

article Full Text OpenAlex 75 FWCI19.54933721