This cluster of papers focuses on Prurigo Pigmentosa, an inflammatory skin disease characterized by distinctive clinicopathological features. The papers cover various aspects including clinicopathological studies, treatment outcomes, association with ketogenic diet and bariatric surgery, epidemiology, and potential links to Helicobacter pylori infection. They also discuss the histopathological characteristics and the efficacy of treatments such as doxycycline. The cluster reflects a comprehensive exploration of this underdiagnosed disease.