专题:Calpain Protease Function and Regulation

This cluster of papers explores the role of calpain, a calcium-dependent protease, in regulating various cellular processes such as cell migration, neurodegeneration, apoptosis, and its involvement in diseases including diabetes, cancer, and cardiovascular remodeling. The papers also discuss the structure, activation, and inhibition of calpain as a potential therapeutic target.
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The concept of intrinsic versus extrinsic apoptosis

article Full Text OpenAlex 319 FWCI23.2145

Mitochondrial calpain-1 activates NLRP3 inflammasome by cleaving ATP5A1 and inducing mitochondrial ROS in CVB3-induced myocarditis

article Full Text OpenAlex 141 FWCI14.5533

Molecular Mechanisms of Macroautophagy, Microautophagy, and Chaperone-Mediated Autophagy

article Full Text OpenAlex 140 FWCI27.8919

Nanoparticles incorporated in nanofibers using electrospinning: A novel nano-in-nano delivery system

review Full Text OpenAlex 123 FWCI9.0387

Endoplasmic Reticulum Stress Signaling and Neuronal Cell Death

review Full Text OpenAlex 99 FWCI9.1973

Protective role of chaperone-mediated autophagy against atherosclerosis

article Full Text OpenAlex 93 FWCI12.5424

Calcium’s Role in Orchestrating Cancer Apoptosis: Mitochondrial-Centric Perspective

review Full Text OpenAlex 83 FWCI15.8606

Chaperone‐mediated autophagy: Molecular mechanisms, biological functions, and diseases

review Full Text OpenAlex 82 FWCI16.4644

Mechanisms Controlling the Expression and Secretion of BDNF

review Full Text OpenAlex 73 FWCI9.9634

Oxeiptosis: a novel pathway of melanocytes death in response to oxidative stress in vitiligo

article Full Text OpenAlex 65 FWCI6.6363