专题:Calpain Protease Function and Regulation

This cluster of papers explores the role of calpain, a calcium-dependent protease, in regulating various cellular processes such as cell migration, neurodegeneration, apoptosis, and its involvement in diseases including diabetes, cancer, and cardiovascular remodeling. The papers also discuss the structure, activation, and inhibition of calpain as a potential therapeutic target.
最新文献
Detection of TAFI 1040C>T rs1926447 Gene Polymorphism in Type 2 Diabetes Mellitus Iraqi Patients

article Full Text OpenAlex

Calpain-2 Regulates Kinesin and Dynein Dysfunction in Neurotoxin-Induced Motoneuron Injury

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Mechanisms of Calcium Absorption and Factors Affecting Bioavailability: A Review

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CATHEPSIN D: MOLECULAR, GENETIC AND FUNCTIONAL ASPECTS IN THE TUMOR MICROENVIRONMENT

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Synergistic therapeutic potential of curcumin and metformin: a multi-pathway approach to disease management

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Starvation induces a transition from autophagy to apoptosis via the ER-Ca2+-calpain signaling axis in the fat body of Bombyx mori

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Predictive Modeling of Cathepsin K Inhibitors Bioactivity for Osteoporosis Treatment by using Grey Wolf Optimizer-Support Vector Machine

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Candidate Interaction Partners of Calpain-5 Suggest Clues to Its Involvement in Neovascular Inflammatory Vitreoretinopathy

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Short linear motifs - Unexplored players driving Toxoplasma gondii infection

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Perinatal management of a pregnant patient with limb-girdle muscular dystrophy R1 calpain3-related

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近5年高被引文献
Mitochondrial calpain-1 activates NLRP3 inflammasome by cleaving ATP5A1 and inducing mitochondrial ROS in CVB3-induced myocarditis

article Full Text OpenAlex 119 FWCI20.40614531

Nanoparticles incorporated in nanofibers using electrospinning: A novel nano-in-nano delivery system

review Full Text OpenAlex 115 FWCI14.73221043

Molecular Mechanisms of Macroautophagy, Microautophagy, and Chaperone-Mediated Autophagy

article Full Text OpenAlex 105 FWCI37.07071163

Protective role of chaperone-mediated autophagy against atherosclerosis

article Full Text OpenAlex 80 FWCI17.95372867

Endoplasmic Reticulum Stress Signaling and Neuronal Cell Death

review Full Text OpenAlex 78 FWCI12.57018551

Calcium’s Role in Orchestrating Cancer Apoptosis: Mitochondrial-Centric Perspective

review Full Text OpenAlex 67 FWCI16.59078989

Chaperone‐mediated autophagy: Molecular mechanisms, biological functions, and diseases

review Full Text OpenAlex 63 FWCI22.24242698

Mechanisms Controlling the Expression and Secretion of BDNF

review Full Text OpenAlex 60 FWCI12.61991716

PCSK9 inhibition protects against myocardial ischemia-reperfusion injury via suppressing autophagy

article Full Text OpenAlex 58 FWCI13.24087489

Oxeiptosis: a novel pathway of melanocytes death in response to oxidative stress in vitiligo

article Full Text OpenAlex 57 FWCI9.30520226