专题:Calpain Protease Function and Regulation

This cluster of papers explores the role of calpain, a calcium-dependent protease, in regulating various cellular processes such as cell migration, neurodegeneration, apoptosis, and its involvement in diseases including diabetes, cancer, and cardiovascular remodeling. The papers also discuss the structure, activation, and inhibition of calpain as a potential therapeutic target.
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匹伐他汀对糖尿病肾脏疾病大鼠刺猬信号通路及肾纤维化的影响

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CHIP protects rheumatoid arthritis progression by targeting TRAF6 in arthritis animal models

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Retraction: In silico investigation of novel Plasmodium Falciparum glycogen synthase kinase (pfGSk3β) inhibitors for the treatment of malaria infection

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Association of PLAG1 and HSP70 Gene Polymorphisms with Morphometric Traits in Female Bali Cattle (Bos javanicus) from East Kalimantan, Indonesia

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Beef carcass electrical stimulation enhances Calpain-1 autolysis but not proteolysis

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Association of PLAG1 and HSP70 Gene Polymorphisms with Morphometric Traits in Female Bali Cattle (Bos javanicus) from East Kalimantan, Indonesia

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Regulation of calpain 1 and calpain 2 activity by dopamine in rat brain regions.

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Caspase-6 Structure and Dynamics by NMR: Uncovering the Complex Motion of a Protease Involved in Neurodegeneration

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A network distribution model of Ca2+ blink in cardiac myocytes

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Robust tauopathy and memory deficits in a mouse model constitutively overexpressing human P301L MAPT

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