专题：Calpain Protease Function and Regulation

This cluster of papers explores the role of calpain, a calcium-dependent protease, in regulating various cellular processes such as cell migration, neurodegeneration, apoptosis, and its involvement in diseases including diabetes, cancer, and cardiovascular remodeling. The papers also discuss the structure, activation, and inhibition of calpain as a potential therapeutic target.
最新文献
CHK2 kınaz domain mutantlarının moleküler dınamık sımülasyonları

dissertation Full Text OpenAlex

Functional assessment of prevalent kelch13 mutations reveals high-level artemisinin resistance potential in Bangladeshi Plasmodium falciparum

article Full Text OpenAlex

Susceptibility and Disease Progression in Calomys callosus: A Robust Rodent Model for Investigating Malaria-related Anemia

preprint Full Text OpenAlex

Peptide Regulation of SERCA Calcium Transport Cycle: Functional Properties and Energetics.

dissertation Full Text OpenAlex

A Sensitive Green-Red FRET Sensor for Calpain-1 Utilizing Heterodimeric Fluorescent Proteins from Distinct Evolutionary Origins

article Full Text OpenAlex

Fazirsiran Unveiled: Methodological Considerations for Optimizing Treatment in Alpha-1 Antitrypsin Deficiency Reply

article Full Text OpenAlex

Piezo1 activation promotes intervertebral disc degeneration via the calpain-2/BAX/caspase-3 apoptosis signaling axis

article Full Text OpenAlex

Alteration of Mitochondrial Ca2+ Fluxes by Kaempferol and CGP-37157 Regulates Ca2+ Oscillations in Human Alveolar Type 2 A549 Cells.

article Full Text OpenAlex

Corrigendum to “Exendin-4 alleviates Aβ1-40-induced apoptosis and calcium dysregulation in RPE cells through the CHP1/NHE1 complex” [Biochem. Pharmacol. 247 (2026) 117789]

article Full Text OpenAlex

Differential expression of mitochondria-associated genes in clinical samples of Plasmodium falciparum showing severe manifestations

article Full Text OpenAlex

近5年高被引文献
The concept of intrinsic versus extrinsic apoptosis

article Full Text OpenAlex 286 FWCI23.0042

Mitochondrial calpain-1 activates NLRP3 inflammasome by cleaving ATP5A1 and inducing mitochondrial ROS in CVB3-induced myocarditis

article Full Text OpenAlex 129 FWCI14.5905

Nanoparticles incorporated in nanofibers using electrospinning: A novel nano-in-nano delivery system

review Full Text OpenAlex 118 FWCI8.9444

Molecular Mechanisms of Macroautophagy, Microautophagy, and Chaperone-Mediated Autophagy

article Full Text OpenAlex 114 FWCI24.8307

Protective role of chaperone-mediated autophagy against atherosclerosis

article Full Text OpenAlex 85 FWCI12.4691

Endoplasmic Reticulum Stress Signaling and Neuronal Cell Death

review Full Text OpenAlex 82 FWCI9.0602

Calcium’s Role in Orchestrating Cancer Apoptosis: Mitochondrial-Centric Perspective

review Full Text OpenAlex 73 FWCI15.5408

Chaperone‐mediated autophagy: Molecular mechanisms, biological functions, and diseases

review Full Text OpenAlex 72 FWCI15.7713

Mechanisms Controlling the Expression and Secretion of BDNF

review Full Text OpenAlex 66 FWCI10.0587

Oxeiptosis: a novel pathway of melanocytes death in response to oxidative stress in vitiligo

article Full Text OpenAlex 61 FWCI6.6533