专题：Calpain Protease Function and Regulation

This cluster of papers explores the role of calpain, a calcium-dependent protease, in regulating various cellular processes such as cell migration, neurodegeneration, apoptosis, and its involvement in diseases including diabetes, cancer, and cardiovascular remodeling. The papers also discuss the structure, activation, and inhibition of calpain as a potential therapeutic target.
最新文献
The calpain-mediated proteolytic cleavage peptide P10 modulates Tau phosphorylation in Alzheimer’s disease

book-chapter Full Text OpenAlex

Retrograde transport of neurotrophin receptor TrkB-FL induced by excitotoxicity regulates Golgi stability and is a target for stroke neuroprotection

article Full Text OpenAlex

Calcium signaling dysregulation in rheumatoid arthritis: a comparative perspective with osteoarthritis

review Full Text OpenAlex

Calpain-2 facilitates infection of the intracellular bacteria Listeria monocytogenes and invasion intestinal immune barrier by impairing nitric oxide homeostasis

article Full Text OpenAlex

Identification of potential roles of cathepsin L1 in the response to alkaline treatment in Macrobrachium nipponense

article Full Text OpenAlex

Serum LDH and NLR as Diagnostic Biomarkers for Drooling in Parkinson's Disease

preprint Full Text OpenAlex

Histidine deficiency-induced hepatic steatosis in teleost fish probably linked to the formimidoyltransferase cyclodeaminase

article Full Text OpenAlex

Oral Pathobionts Aggravate Myocardial Infarction Through Mobilization of B2 Cells

article Full Text OpenAlex

Hypoxia suppressed the Siglec-5 signaling in TAMs via modulating the balance of SHP2/SYK activation in hepatocellular carcinoma

article Full Text OpenAlex

Studying the Vascular Tone of Mouse Aortic Rings in a Standard Wire Myograph

book-chapter Full Text OpenAlex

近5年高被引文献
Role of Oxidative Stress in Reperfusion following Myocardial Ischemia and Its Treatments

review Full Text OpenAlex 205 FWCI8.327

Deficient Chaperone-Mediated Autophagy Promotes Inflammation and Atherosclerosis

article Full Text OpenAlex 133 FWCI17.766

Mitochondrial calpain-1 activates NLRP3 inflammasome by cleaving ATP5A1 and inducing mitochondrial ROS in CVB3-induced myocarditis

article Full Text OpenAlex 99 FWCI13.764

Boceprevir, Calpain Inhibitors II and XII, and GC-376 Have Broad-Spectrum Antiviral Activity against Coronaviruses

article Full Text OpenAlex 97 FWCI10.566

Nanoparticles incorporated in nanofibers using electrospinning: A novel nano-in-nano delivery system

review Full Text OpenAlex 96 FWCI2.066

Endothelial LRP1 protects against neurodegeneration by blocking cyclophilin A

article Full Text OpenAlex 94 FWCI6.46

High glucose induces Drp1-mediated mitochondrial fission via the Orai1 calcium channel to participate in diabetic cardiomyocyte hypertrophy

article Full Text OpenAlex 86 FWCI12.5

Macrophage NFATc3 prevents foam cell formation and atherosclerosis: evidence and mechanisms

article Full Text OpenAlex 85 FWCI5.215

Molecular Mechanisms of Macroautophagy, Microautophagy, and Chaperone-Mediated Autophagy

article Full Text OpenAlex 72 FWCI22.702

Molecular chaperones and Parkinson's disease

review Full Text OpenAlex 72 FWCI1.61