专题：Nuclear Receptors and Signaling

This cluster of papers explores the Nurr1/CoREST pathway and its role in protecting dopaminergic neurons from inflammation-induced death, with implications for neurodegenerative diseases such as Parkinson's. The research covers topics such as mitochondrial targeting, nuclear receptors, transcriptional regulation, and apoptosis.
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Molecular docking as a tool for the discovery of molecular targets of nutraceuticals in diseases management

review Full Text OpenAlex 941 FWCI189.586

Signaling pathways and targeted therapy for myocardial infarction

review Full Text OpenAlex 748 FWCI60.1771

The pathogenesis of Parkinson's disease

review Full Text OpenAlex 726 FWCI274.5099

Assessment of heterogeneity among participants in the Parkinson's Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study

article Full Text OpenAlex 626 FWCI130.2536

Multiple sclerosis progression: time for a new mechanism-driven framework

review Full Text OpenAlex 545 FWCI72.6419

Signaling pathways in Parkinson’s disease: molecular mechanisms and therapeutic interventions

review Full Text OpenAlex 372 FWCI56.8872

Cholesterol and matrisome pathways dysregulated in astrocytes and microglia

article Full Text OpenAlex 368 FWCI43.3285

Trial of Prasinezumab in Early-Stage Parkinson’s Disease

article Full Text OpenAlex 367 FWCI43.73

FSH blockade improves cognition in mice with Alzheimer’s disease

article Full Text OpenAlex 329 FWCI31.478

APOE4 homozygosity represents a distinct genetic form of Alzheimer’s disease

article Full Text OpenAlex 295 FWCI99.5066