专题：Nuclear Receptors and Signaling

This cluster of papers explores the Nurr1/CoREST pathway and its role in protecting dopaminergic neurons from inflammation-induced death, with implications for neurodegenerative diseases such as Parkinson's. The research covers topics such as mitochondrial targeting, nuclear receptors, transcriptional regulation, and apoptosis.
最新文献
MARCH5 Promotes Cardiac Hypertrophy by Regulating Akt/mTOR/Gsk‐3β/GATA4 Signalling Pathway

article Full Text OpenAlex

The Alzheimer's-Associated SORL1 p.Y1816C Variant Impairs APP Sorting, Axonal Trafficking, and Neuronal Activity in iPSC-Derived Brain Models

preprint Full Text OpenAlex

Nuclear receptors in health and disease: signaling pathways, biological functions and pharmaceutical interventions

review Full Text OpenAlex

In vivo measurement of an Apelin gradient with a genetically encoded APLNR conformation biosensor

article Full Text OpenAlex

Parkinson’s Disease: Bridging Gaps, Building Biomarkers, and Reimagining Clinical Translation

preprint Full Text OpenAlex

Targeting CD37 promotes macrophage-dependent phagocytosis of multiple cancer cell types and facilitates tumor clearance in mice

article Full Text OpenAlex

An Insight into Long‐Term Outcomes in a Parkinson's Disease Minor Phenomena Cohort

letter Full Text OpenAlex

Triple Assessments of Atherosclerosis in Patients With Heterozygous Familial Hypercholesterolemia

article Full Text OpenAlex

Parkinson’s disease: genetics and neuroinflammatory insights

review Full Text OpenAlex

Robust Increase in IQCK Protein Expression in Mouse Models of Alzheimer's Disease and iPSC‐Derived Neurons

article Full Text OpenAlex

近5年高被引文献
Molecular docking as a tool for the discovery of molecular targets of nutraceuticals in diseases management

review Full Text OpenAlex 572 FWCI25.559

Signaling pathways and targeted therapy for myocardial infarction

review Full Text OpenAlex 557 FWCI19.259

Assessment of heterogeneity among participants in the Parkinson's Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study

article Full Text OpenAlex 455 FWCI130.806

The pathogenesis of Parkinson's disease

review Full Text OpenAlex 428 FWCI112.107

Microglia in Neuroinflammation and Neurodegeneration: From Understanding to Therapy

review Full Text OpenAlex 402 FWCI10.806

Multiple sclerosis progression: time for a new mechanism-driven framework

review Full Text OpenAlex 401 FWCI21.126

GDF15: emerging biology and therapeutic applications for obesity and cardiometabolic disease

review Full Text OpenAlex 359 FWCI13.279

Oxidative stress and regulated cell death in Parkinson’s disease

review Full Text OpenAlex 326 FWCI9.191

Trial of Prasinezumab in Early-Stage Parkinson’s Disease

article Full Text OpenAlex 301 FWCI47.468

Progress towards therapies for disease modification in Parkinson's disease

review Full Text OpenAlex 290 FWCI7.726