专题：Nuclear Receptors and Signaling

This cluster of papers explores the Nurr1/CoREST pathway and its role in protecting dopaminergic neurons from inflammation-induced death, with implications for neurodegenerative diseases such as Parkinson's. The research covers topics such as mitochondrial targeting, nuclear receptors, transcriptional regulation, and apoptosis.
最新文献
Parkinson's disease: pathogenesis and therapeutic strategies

article Full Text OpenAlex

Quemliclustat and chemotherapy with or without zimberelimab in metastatic pancreatic adenocarcinoma: a randomized phase 1 trial

article Full Text OpenAlex

Research progress on employing medicinal plants and their active compounds to target autophagic pathways for Parkinson's disease therapy

article Full Text OpenAlex

Adult Neurogenesis in Neurodegenerative Diseases: Mechanisms of Dysregulation in Alzheimer’s and Parkinson’s Disease

article Full Text OpenAlex

Mechanistic insights into cannabidiol-mediated TrkB activation via FRS2 interaction in attenuating Alzheimer’s disease pathology and cognitive impairment

article Full Text OpenAlex

Putamen dopamine synthesis, vesicular storage, and metabolism in Parkinson disease

article Full Text OpenAlex

Nuclear factor erythroid 2-related factor 2 induction abrogates mitochondrial stress through parkin regulation

article Full Text OpenAlex

Cochlear macrophage CD74 enhances the apoptosis of senescent cochlear hair cells by down-regulating MIF

article Full Text OpenAlex

Nuclear receptor subfamily 4 group a member 2 induces a Warburg-like effect and promotes phospholipids synthesis in the mouse heart

article Full Text OpenAlex

Methylglyoxal Affects Dopamine Homeostasis in SH‐SY5Y Cells Through the Modulation of miR‐190a and miR‐214

article Full Text OpenAlex

近5年高被引文献
Molecular docking as a tool for the discovery of molecular targets of nutraceuticals in diseases management

review Full Text OpenAlex 1000 FWCI193.1389

The pathogenesis of Parkinson's disease

review Full Text OpenAlex 801 FWCI275.3408

Signaling pathways and targeted therapy for myocardial infarction

review Full Text OpenAlex 783 FWCI60.1486

Multiple sclerosis progression: time for a new mechanism-driven framework

review Full Text OpenAlex 577 FWCI72.2948

Signaling pathways in Parkinson’s disease: molecular mechanisms and therapeutic interventions

review Full Text OpenAlex 404 FWCI57.7676

Cholesterol and matrisome pathways dysregulated in astrocytes and microglia

article Full Text OpenAlex 386 FWCI43.7688

Trial of Prasinezumab in Early-Stage Parkinson’s Disease

article Full Text OpenAlex 378 FWCI43.4697

FSH blockade improves cognition in mice with Alzheimer’s disease

article Full Text OpenAlex 337 FWCI31.4496

Transcriptome‐level discovery of survival‐associated biomarkers and therapy targets in non‐small‐cell lung cancer

article Full Text OpenAlex 333 FWCI56.7046

Trial of Cinpanemab in Early Parkinson’s Disease

article Full Text OpenAlex 320 FWCI37.2774