This cluster of papers encompasses a wide range of research on the artichoke (Cynara cardunculus), focusing on its potential as a functional food, nutraceutical source, and biomass crop. The studies cover topics such as the identification and quantification of phenolic compounds, antioxidant activities, genetic diversity, health benefits, and hepatoprotective activity. Additionally, the research explores the cultivation and industrial applications of artichoke, as well as its potential in managing metabolic syndrome.