专题：Neurological Disease Mechanisms and Treatments

This cluster of papers focuses on chronic cerebral hypoperfusion and its association with neurodegenerative diseases, vascular cognitive impairment, white matter lesions, and oxidative stress. The research includes experimental models, glial activation, memory impairment, and the neuroprotective effects of various compounds.
最新文献
Identification of senescent, TREM2-expressing microglia in aging and Alzheimer’s disease model mouse brain

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Metformin attenuates white matter microstructural changes in Alzheimer’s disease

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Effect of scutellarin on BV-2 microglial-mediated apoptosis in PC12 cells via JAK2/STAT3 signalling pathway

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A novel rat model of cerebral small vessel disease based on vascular risk factors of hypertension, aging, and cerebral hypoperfusion

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Fabrication of blueberry anthocyanins–rich gels based on the apricot polysaccharides with different esterification degrees

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The Neuroprotective Effects of Oroxylum indicum Extract in SHSY-5Y Neuronal Cells by Upregulating BDNF Gene Expression under LPS Induced Inflammation

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Single-cell sequencing of the substantia nigra reveals microglial activation in a model of MPTP

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Greater White Matter Hyperintensity Volume Is Associated with the Number of Microhemorrhages in Preclinical Alzheimer's Disease

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Cerebral arteriolosclerosis, lacunar infarcts, and cognition in older Black adults

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Efficacy and safety of butylphthalide in patients with mild cognitive impairment: a multicentre, randomised, double-blind, placebo-controlled trial (EBMCI study)

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近5年高被引文献
Neuroimaging standards for research into small vessel disease—advances since 2013

review Full Text OpenAlex 724 FWCI243.58473958

Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions

review Full Text OpenAlex 671 FWCI90.15822629

Four distinct trajectories of tau deposition identified in Alzheimer’s disease

article Full Text OpenAlex 659 FWCI84.02800813

Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer’s disease

article Full Text OpenAlex 634 FWCI86.65954885

Differences Between Plasma and Cerebrospinal Fluid Glial Fibrillary Acidic Protein Levels Across the Alzheimer Disease Continuum

article Full Text OpenAlex 531 FWCI61.02414279

ApoE in Alzheimer’s disease: pathophysiology and therapeutic strategies

review Full Text OpenAlex 530 FWCI95.1330755

Blood-Brain Barrier Dysfunction Amplifies the Development of Neuroinflammation: Understanding of Cellular Events in Brain Microvascular Endothelial Cells for Prevention and Treatment of BBB Dysfunction

review Full Text OpenAlex 497 FWCI39.53295118

Prediction of future Alzheimer’s disease dementia using plasma phospho-tau combined with other accessible measures

article Full Text OpenAlex 485 FWCI76.54680172

Hypertension-induced cognitive impairment: from pathophysiology to public health

review Full Text OpenAlex 480 FWCI48.1491072

Microglial activation and tau propagate jointly across Braak stages

article Full Text OpenAlex 473 FWCI48.78264809