专题：Clusterin in disease pathology

This cluster of papers explores the multifaceted role of Clusterin, a chaperone protein, in cancer development, progression, and therapy. It investigates its involvement in apoptosis inhibition, TGF-ß signaling modulation, angiogenesis promotion, chemoresistance, and its potential as a biomarker for various cancers. The papers also discuss the implications of Clusterin in metastasis, particularly in prostate cancer.
最新文献
Inhibition of Activin A Signaling by Follistatin Alleviates Diabetic Kidney Disease Burden

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Serum levels of leucine-rich α–2 glycoprotein 1 (LRG1), pro-neurotensin (PNT), fatty acid-binding protein 4 (FABP4) and furin in pediatric growth hormone deficiency before and after 1-year growth hormone replacement therapy

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Correction to: Establishment of blood glycosidase activities and their excursions in sepsis

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Correction to: A Role for Leucine-Rich α2-Glycoprotein in Leukocyte Trafficking and Mucosal Inflammation in Inflammatory Bowel Disease

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Figure 2 from Plasma Proteomic Analysis Reveals Complement System Changes in Irradiated Female BALB/c Mice during Mammary Carcinogenesis

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Figure 1 from Plasma Proteomic Analysis Reveals Complement System Changes in Irradiated Female BALB/c Mice during Mammary Carcinogenesis

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Leveraging Artificial Intelligence in Studying Inflammation-driven Leukemogenesis: A New Frontier in Predicting Malignant Tumour Shifts

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Secreted Clusterin Inhibits Keloid Formation by Promoting Fibroblast Apoptosis

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Neuroprotective mechanism of salidroside derivative SHPL-49 involves amelioration of brain lipid metabolism disorder to mitigate ferroptosis in a rat model of pMCAO

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Figure 4 from Plasma Proteomic Analysis Reveals Complement System Changes in Irradiated Female BALB/c Mice during Mammary Carcinogenesis

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近5年高被引文献
Exercise plasma boosts memory and dampens brain inflammation via clusterin

article Full Text OpenAlex 304 FWCI23.948

LRG1: an emerging player in disease pathogenesis

review Full Text OpenAlex 130 FWCI5.456

Pathologically high intraocular pressure disturbs normal iron homeostasis and leads to retinal ganglion cell ferroptosis in glaucoma

article Full Text OpenAlex 126 FWCI12.127

Tubular epithelial cell-to-macrophage communication forms a negative feedback loop via extracellular vesicle transfer to promote renal inflammation and apoptosis in diabetic nephropathy

article Full Text OpenAlex 124 FWCI9.234

Inflammation, Extracellular Matrix Remodeling, and Proteostasis in Tumor Microenvironment

review Full Text OpenAlex 106 FWCI3.012

Topological data analysis in biomedicine: A review

review Full Text OpenAlex 100 FWCI2.964

An integrative multi-omics approach reveals new central nervous system pathway alterations in Alzheimer’s disease

article Full Text OpenAlex 82 FWCI9.611

N-cadherin upregulation mediates adaptive radioresistance in glioblastoma

article Full Text OpenAlex 82 FWCI6.697

Clonal Hematopoiesis of Indeterminate Potential Predicts Adverse Outcomes in Patients With Atherosclerotic Cardiovascular Disease

article Full Text OpenAlex 82 FWCI31.728

Clusterin secreted from astrocyte promotes excitatory synaptic transmission and ameliorates Alzheimer’s disease neuropathology

article Full Text OpenAlex 81 FWCI6.799