专题：Clusterin in disease pathology

This cluster of papers explores the multifaceted role of Clusterin, a chaperone protein, in cancer development, progression, and therapy. It investigates its involvement in apoptosis inhibition, TGF-ß signaling modulation, angiogenesis promotion, chemoresistance, and its potential as a biomarker for various cancers. The papers also discuss the implications of Clusterin in metastasis, particularly in prostate cancer.
最新文献
Research Progress on the Promotion of Human Umbilical Vein Endothelial Cell (HUVECs) angiogenesis by Rhodiola Rosea and Exosomes through SDF-1/CXCR4 under High Glucose Environment

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Exploring the Clinical Utility of Osteoprotegerin in Heart Failure—A Systematic Review and Meta-Analysis

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The Effect of Thyroid Function on GDF15 Levels

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Identification and validation of a Golgi apparatus related gene signature for prognosis prediction and immune microenvironment profiling in colorectal cancer

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Combined inhibition of S100A4 and TIGIT suppresses late-stage breast cancer metastasis

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Complex II inhibition suppresses RSL3-induced ferroptosis by restoring mitochondrial bioenergetics

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B355252 Targets UCP2 to Rescue Intracerebral Hemorrhage-Induced Injury by Promoting Mitochondrial Fusion and Inhibiting Ferroptosis

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Phosphatidylserine Promotes Tighter Membrane Binding of Clusterin Signal Peptide over Phosphatidylglycerol, While Phosphatidylethanolamine Allows Its Deeper Penetration

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Research Progress on Ferroptosis-Related Pathways and the Pathogenic Mechanisms of Epilepsy

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Figure S6 from Lipid Composition Alters Ferroptosis Sensitivity

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近5年高被引文献
Exercise plasma boosts memory and dampens brain inflammation via clusterin

article Full Text OpenAlex 373 FWCI27.7803458

Tubular epithelial cell-to-macrophage communication forms a negative feedback loop via extracellular vesicle transfer to promote renal inflammation and apoptosis in diabetic nephropathy

article Full Text OpenAlex 160 FWCI12.05562176

Pathologically high intraocular pressure disturbs normal iron homeostasis and leads to retinal ganglion cell ferroptosis in glaucoma

article Full Text OpenAlex 158 FWCI19.44492696

LRG1: an emerging player in disease pathogenesis

review Full Text OpenAlex 150 FWCI22.64263366

Topological data analysis in biomedicine: A review

review Full Text OpenAlex 135 FWCI35.28860033

Colorectal cancer-associated fibroblasts promote metastasis by up-regulating LRG1 through stromal IL-6/STAT3 signaling

article Full Text OpenAlex 118 FWCI9.43483442

Inflammation, Extracellular Matrix Remodeling, and Proteostasis in Tumor Microenvironment

review Full Text OpenAlex 110 FWCI8.70101397

Clonal Hematopoiesis of Indeterminate Potential Predicts Adverse Outcomes in Patients With Atherosclerotic Cardiovascular Disease

article Full Text OpenAlex 106 FWCI41.35506471

An integrative multi-omics approach reveals new central nervous system pathway alterations in Alzheimer’s disease

article Full Text OpenAlex 95 FWCI10.86293641

Clusterin secreted from astrocyte promotes excitatory synaptic transmission and ameliorates Alzheimer’s disease neuropathology

article Full Text OpenAlex 89 FWCI7.33820455